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Atrial Myocyte NLRP3/CaMKII Nexus Forms a Substrate for Postoperative Atrial Fibrillation.
Heijman J, Muna AP, Veleva T, Molina CE, Sutanto H, Tekook M, Wang Q, Abu-Taha IH, Gorka M, Künzel S, El-Armouche A, Reichenspurner H, Kamler M, Nikolaev V, Ravens U, Li N, Nattel S, Wehrens XHT, Dobrev D. Heijman J, et al. Among authors: nikolaev v. Circ Res. 2020 Sep 25;127(8):1036-1055. doi: 10.1161/CIRCRESAHA.120.316710. Epub 2020 Jul 30. Circ Res. 2020. PMID: 32762493 Free PMC article.
Phosphodiesterase-2 is up-regulated in human failing hearts and blunts β-adrenergic responses in cardiomyocytes.
Mehel H, Emons J, Vettel C, Wittköpper K, Seppelt D, Dewenter M, Lutz S, Sossalla S, Maier LS, Lechêne P, Leroy J, Lefebvre F, Varin A, Eschenhagen T, Nattel S, Dobrev D, Zimmermann WH, Nikolaev VO, Vandecasteele G, Fischmeister R, El-Armouche A. Mehel H, et al. J Am Coll Cardiol. 2013 Oct 22;62(17):1596-606. doi: 10.1016/j.jacc.2013.05.057. Epub 2013 Jun 26. J Am Coll Cardiol. 2013. PMID: 23810893 Free article.
PDE2-mediated cAMP hydrolysis accelerates cardiac fibroblast to myofibroblast conversion and is antagonized by exogenous activation of cGMP signaling pathways.
Vettel C, Lämmle S, Ewens S, Cervirgen C, Emons J, Ongherth A, Dewenter M, Lindner D, Westermann D, Nikolaev VO, Lutz S, Zimmermann WH, El-Armouche A. Vettel C, et al. Among authors: nikolaev vo. Am J Physiol Heart Circ Physiol. 2014 Apr 15;306(8):H1246-52. doi: 10.1152/ajpheart.00852.2013. Epub 2014 Feb 14. Am J Physiol Heart Circ Physiol. 2014. PMID: 24531807 Free article.
Late INa increases diastolic SR-Ca2+-leak in atrial myocardium by activating PKA and CaMKII.
Fischer TH, Herting J, Mason FE, Hartmann N, Watanabe S, Nikolaev VO, Sprenger JU, Fan P, Yao L, Popov AF, Danner BC, Schöndube F, Belardinelli L, Hasenfuss G, Maier LS, Sossalla S. Fischer TH, et al. Cardiovasc Res. 2015 Jul 1;107(1):184-96. doi: 10.1093/cvr/cvv153. Epub 2015 May 18. Cardiovasc Res. 2015. PMID: 25990311 Free PMC article.
Redox Imaging Using Cardiac Myocyte-Specific Transgenic Biosensor Mice.
Swain L, Kesemeyer A, Meyer-Roxlau S, Vettel C, Zieseniss A, Güntsch A, Jatho A, Becker A, Nanadikar MS, Morgan B, Dennerlein S, Shah AM, El-Armouche A, Nikolaev VO, Katschinski DM. Swain L, et al. Circ Res. 2016 Oct 14;119(9):1004-1016. doi: 10.1161/CIRCRESAHA.116.309551. Epub 2016 Aug 23. Circ Res. 2016. PMID: 27553648
Microdomain-Specific Modulation of L-Type Calcium Channels Leads to Triggered Ventricular Arrhythmia in Heart Failure.
Sanchez-Alonso JL, Bhargava A, O'Hara T, Glukhov AV, Schobesberger S, Bhogal N, Sikkel MB, Mansfield C, Korchev YE, Lyon AR, Punjabi PP, Nikolaev VO, Trayanova NA, Gorelik J. Sanchez-Alonso JL, et al. Among authors: nikolaev vo. Circ Res. 2016 Sep 30;119(8):944-55. doi: 10.1161/CIRCRESAHA.116.308698. Epub 2016 Aug 29. Circ Res. 2016. PMID: 27572487 Free PMC article.
580 results