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Impairment of gamma-glutamyl transferase 1 activity in the metabolic pathogenesis of chromophobe renal cell carcinoma.
Priolo C, Khabibullin D, Reznik E, Filippakis H, Ogórek B, Kavanagh TR, Nijmeh J, Herbert ZT, Asara JM, Kwiatkowski DJ, Wu CL, Henske EP. Priolo C, et al. Among authors: nijmeh j. Proc Natl Acad Sci U S A. 2018 Jul 3;115(27):E6274-E6282. doi: 10.1073/pnas.1710849115. Epub 2018 Jun 11. Proc Natl Acad Sci U S A. 2018. PMID: 29891694 Free PMC article.
p62/SQSTM1 Cooperates with Hyperactive mTORC1 to Regulate Glutathione Production, Maintain Mitochondrial Integrity, and Promote Tumorigenesis.
Lam HC, Baglini CV, Lope AL, Parkhitko AA, Liu HJ, Alesi N, Malinowska IA, Ebrahimi-Fakhari D, Saffari A, Yu JJ, Pereira A, Khabibullin D, Ogorek B, Nijmeh J, Kavanagh T, Handen A, Chan SY, Asara JM, Oldham WM, Diaz-Meco MT, Moscat J, Sahin M, Priolo C, Henske EP. Lam HC, et al. Among authors: nijmeh j. Cancer Res. 2017 Jun 15;77(12):3255-3267. doi: 10.1158/0008-5472.CAN-16-2458. Epub 2017 May 16. Cancer Res. 2017. PMID: 28512249 Free PMC article.
Rapamycin-induced miR-21 promotes mitochondrial homeostasis and adaptation in mTORC1 activated cells.
Lam HC, Liu HJ, Baglini CV, Filippakis H, Alesi N, Nijmeh J, Du H, Lope AL, Cottrill KA, Handen A, Asara JM, Kwiatkowski DJ, Ben-Sahra I, Oldham WM, Chan SY, Henske EP. Lam HC, et al. Among authors: nijmeh j. Oncotarget. 2017 Aug 4;8(39):64714-64727. doi: 10.18632/oncotarget.19947. eCollection 2017 Sep 12. Oncotarget. 2017. PMID: 29029388 Free PMC article.
Emerging biomarkers of lymphangioleiomyomatosis.
Nijmeh J, El-Chemaly S, Henske EP. Nijmeh J, et al. Expert Rev Respir Med. 2018 Feb;12(2):95-102. doi: 10.1080/17476348.2018.1409622. Epub 2017 Dec 1. Expert Rev Respir Med. 2018. PMID: 29171770 Review.
TSC2 regulates microRNA biogenesis via mTORC1 and GSK3β.
Ogórek B, Lam HC, Khabibullin D, Liu HJ, Nijmeh J, Triboulet R, Kwiatkowski DJ, Gregory RI, Henske EP. Ogórek B, et al. Among authors: nijmeh j. Hum Mol Genet. 2018 May 1;27(9):1654-1663. doi: 10.1093/hmg/ddy073. Hum Mol Genet. 2018. PMID: 29509898 Free PMC article.
Loss of FLCN inhibits canonical WNT signaling via TFE3.
Kennedy JC, Khabibullin D, Hougard T, Nijmeh J, Shi W, Henske EP. Kennedy JC, et al. Among authors: nijmeh j. Hum Mol Genet. 2019 Oct 1;28(19):3270-3281. doi: 10.1093/hmg/ddz158. Hum Mol Genet. 2019. PMID: 31272105 Free PMC article.
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