Nijhuis A - Search Results

1

Intestinal fibrosis in Crohn's disease: role of microRNAs as fibrogenic modulators, serum biomarkers, and therapeutic targets.

Lewis A, Nijhuis A, Mehta S, Kumagai T, Feakins R, Lindsay JO, Silver A. Lewis A, et al. Among authors: nijhuis a. Inflamm Bowel Dis. 2015 May;21(5):1141-50. doi: 10.1097/MIB.0000000000000298. Inflamm Bowel Dis. 2015. PMID: 25636122 Review.

2

DUOX2 and DUOXA2 form the predominant enzyme system capable of producing the reactive oxygen species H2O2 in active ulcerative colitis and are modulated by 5-aminosalicylic acid.

MacFie TS, Poulsom R, Parker A, Warnes G, Boitsova T, Nijhuis A, Suraweera N, Poehlmann A, Szary J, Feakins R, Jeffery R, Harper RW, Jubb AM, Lindsay JO, Silver A. MacFie TS, et al. Among authors: nijhuis a. Inflamm Bowel Dis. 2014 Mar;20(3):514-24. doi: 10.1097/01.MIB.0000442012.45038.0e. Inflamm Bowel Dis. 2014. PMID: 24492313

3

In Crohn's disease fibrosis-reduced expression of the miR-29 family enhances collagen expression in intestinal fibroblasts.

Nijhuis A, Biancheri P, Lewis A, Bishop CL, Giuffrida P, Chan C, Feakins R, Poulsom R, Di Sabatino A, Corazza GR, MacDonald TT, Lindsay JO, Silver AR. Nijhuis A, et al. Clin Sci (Lond). 2014 Sep;127(5):341-50. doi: 10.1042/CS20140048. Clin Sci (Lond). 2014. PMID: 24641356

4

Defects in the adherens junction complex (E-cadherin/ β-catenin) in inflammatory bowel disease.

Mehta S, Nijhuis A, Kumagai T, Lindsay J, Silver A. Mehta S, et al. Among authors: nijhuis a. Cell Tissue Res. 2015 Jun;360(3):749-60. doi: 10.1007/s00441-014-1994-6. Epub 2014 Sep 20. Cell Tissue Res. 2015. PMID: 25238996 Review.

5

Low Serum Levels of MicroRNA-19 Are Associated with a Stricturing Crohn's Disease Phenotype.

Lewis A, Mehta S, Hanna LN, Rogalski LA, Jeffery R, Nijhuis A, Kumagai T, Biancheri P, Bundy JG, Bishop CL, Feakins R, Di Sabatino A, Lee JC, Lindsay JO, Silver A. Lewis A, et al. Among authors: nijhuis a. Inflamm Bowel Dis. 2015 Aug;21(8):1926-34. doi: 10.1097/MIB.0000000000000443. Inflamm Bowel Dis. 2015. PMID: 25985247

6

Role of Reactive Oxygen Species in the Abrogation of Oxaliplatin Activity by Cetuximab in Colorectal Cancer.

Santoro V, Jia R, Thompson H, Nijhuis A, Jeffery R, Kiakos K, Silver AR, Hartley JA, Hochhauser D. Santoro V, et al. Among authors: nijhuis a. J Natl Cancer Inst. 2015 Dec 30;108(6):djv394. doi: 10.1093/jnci/djv394. Print 2016 Jun. J Natl Cancer Inst. 2015. PMID: 26719345 Free PMC article.

7

MCL-1 is modulated in Crohn's disease fibrosis by miR-29b via IL-6 and IL-8.

Nijhuis A, Curciarello R, Mehta S, Feakins R, Bishop CL, Lindsay JO, Silver A. Nijhuis A, et al. Cell Tissue Res. 2017 May;368(2):325-335. doi: 10.1007/s00441-017-2576-1. Epub 2017 Feb 11. Cell Tissue Res. 2017. PMID: 28190086 Free PMC article.

8

Remodelling of microRNAs in colorectal cancer by hypoxia alters metabolism profiles and 5-fluorouracil resistance.

Nijhuis A, Thompson H, Adam J, Parker A, Gammon L, Lewis A, Bundy JG, Soga T, Jalaly A, Propper D, Jeffery R, Suraweera N, McDonald S, Thaha MA, Feakins R, Lowe R, Bishop CL, Silver A. Nijhuis A, et al. Hum Mol Genet. 2017 Apr 15;26(8):1552-1564. doi: 10.1093/hmg/ddx059. Hum Mol Genet. 2017. PMID: 28207045 Free PMC article.

9

GPER mediates differential effects of estrogen on colon cancer cell proliferation and migration under normoxic and hypoxic conditions.

Bustos V, Nolan ÁM, Nijhuis A, Harvey H, Parker A, Poulsom R, McBryan J, Thomas W, Silver A, Harvey BJ. Bustos V, et al. Among authors: nijhuis a. Oncotarget. 2017 Sep 6;8(48):84258-84275. doi: 10.18632/oncotarget.20653. eCollection 2017 Oct 13. Oncotarget. 2017. PMID: 29137421 Free PMC article.

10

Epithelial down-regulation of the miR-200 family in fibrostenosing Crohn's disease is associated with features of epithelial to mesenchymal transition.

Mehta SJ, Lewis A, Nijhuis A, Jeffery R, Biancheri P, Di Sabatino A, Feakins R, Silver A, Lindsay JO. Mehta SJ, et al. Among authors: nijhuis a. J Cell Mol Med. 2018 Nov;22(11):5617-5628. doi: 10.1111/jcmm.13836. Epub 2018 Sep 6. J Cell Mol Med. 2018. PMID: 30188001 Free PMC article.

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