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Podocyte Injury in Diabetic Kidney Disease in Mouse Models Involves TRPC6-mediated Calpain Activation Impairing Autophagy.
Salemkour Y, Yildiz D, Dionet L, 't Hart DC, Verheijden KAT, Saito R, Mahtal N, Delbet JD, Letavernier E, Rabant M, Karras A, van der Vlag J, Nijenhuis T, Tharaux PL, Lenoir O. Salemkour Y, et al. Among authors: nijenhuis t. J Am Soc Nephrol. 2023 Nov 1;34(11):1823-1842. doi: 10.1681/ASN.0000000000000212. Epub 2023 Sep 6. J Am Soc Nephrol. 2023. PMID: 37678257
Angiotensin II contributes to podocyte injury by increasing TRPC6 expression via an NFAT-mediated positive feedback signaling pathway.
Nijenhuis T, Sloan AJ, Hoenderop JG, Flesche J, van Goor H, Kistler AD, Bakker M, Bindels RJ, de Boer RA, Möller CC, Hamming I, Navis G, Wetzels JF, Berden JH, Reiser J, Faul C, van der Vlag J. Nijenhuis T, et al. Am J Pathol. 2011 Oct;179(4):1719-32. doi: 10.1016/j.ajpath.2011.06.033. Epub 2011 Aug 11. Am J Pathol. 2011. PMID: 21839714 Free PMC article.
New TRPC6 gain-of-function mutation in a non-consanguineous Dutch family with late-onset focal segmental glomerulosclerosis.
Hofstra JM, Lainez S, van Kuijk WH, Schoots J, Baltissen MP, Hoefsloot LH, Knoers NV, Berden JH, Bindels RJ, van der Vlag J, Hoenderop JG, Wetzels JF, Nijenhuis T. Hofstra JM, et al. Among authors: nijenhuis t. Nephrol Dial Transplant. 2013 Jul;28(7):1830-8. doi: 10.1093/ndt/gfs572. Epub 2013 Jan 4. Nephrol Dial Transplant. 2013. PMID: 23291369
1,25-Vitamin D3 Deficiency Induces Albuminuria.
Sonneveld R, Hoenderop JG, Stavenuiter AW, Ferrantelli E, Baltissen MP, Dijkman HB, Florquin S, Rops AL, Wetzels JF, Berden JH, van der Vlag J, Nijenhuis T. Sonneveld R, et al. Among authors: nijenhuis t. Am J Pathol. 2016 Apr;186(4):794-804. doi: 10.1016/j.ajpath.2015.11.015. Epub 2016 Feb 3. Am J Pathol. 2016. PMID: 26851346 Free article.
72 results