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TGF-β2 is an exercise-induced adipokine that regulates glucose and fatty acid metabolism.
Takahashi H, Alves CRR, Stanford KI, Middelbeek RJW, Nigro P, Ryan RE, Xue R, Sakaguchi M, Lynes MD, So K, Mul JD, Lee MY, Balan E, Pan H, Dreyfuss JM, Hirshman MF, Azhar M, Hannukainen JC, Nuutila P, Kalliokoski KK, Nielsen S, Pedersen BK, Kahn CR, Tseng YH, Goodyear LJ. Takahashi H, et al. Among authors: nigro p. Nat Metab. 2019 Feb;1(2):291-303. doi: 10.1038/s42255-018-0030-7. Epub 2019 Feb 11. Nat Metab. 2019. PMID: 31032475 Free PMC article.
FGF6 and FGF9 regulate UCP1 expression independent of brown adipogenesis.
Shamsi F, Xue R, Huang TL, Lundh M, Liu Y, Leiria LO, Lynes MD, Kempf E, Wang CH, Sugimoto S, Nigro P, Landgraf K, Schulz T, Li Y, Emanuelli B, Kothakota S, Williams LT, Jessen N, Pedersen SB, Böttcher Y, Blüher M, Körner A, Goodyear LJ, Mohammadi M, Kahn CR, Tseng YH. Shamsi F, et al. Among authors: nigro p. Nat Commun. 2020 Mar 17;11(1):1421. doi: 10.1038/s41467-020-15055-9. Nat Commun. 2020. PMID: 32184391 Free PMC article.
Exercise intensity regulates cytokine and klotho responses in men.
Middelbeek RJW, Motiani P, Brandt N, Nigro P, Zheng J, Virtanen KA, Kalliokoski KK, Hannukainen JC, Goodyear LJ. Middelbeek RJW, et al. Among authors: nigro p. Nutr Diabetes. 2021 Jan 7;11(1):5. doi: 10.1038/s41387-020-00144-x. Nutr Diabetes. 2021. PMID: 33414377 Free PMC article. Clinical Trial.
Exercise Training Promotes Sex-Specific Adaptations in Mouse Inguinal White Adipose Tissue.
Nigro P, Middelbeek RJW, Alves CRR, Rovira-Llopis S, Ramachandran K, Rowland LA, Møller AB, Takahashi H, Alves-Wagner AB, Vamvini M, Makarewicz NS, Albertson BG, Hirshman MF, Goodyear LJ. Nigro P, et al. Diabetes. 2021 Jun;70(6):1250-1264. doi: 10.2337/db20-0790. Epub 2021 Feb 9. Diabetes. 2021. PMID: 33563587 Free PMC article.
Single-cell dissection of the obesity-exercise axis in adipose-muscle tissues implies a critical role for mesenchymal stem cells.
Yang J, Vamvini M, Nigro P, Ho LL, Galani K, Alvarez M, Tanigawa Y, Renfro A, Carbone NP, Laakso M, Agudelo LZ, Pajukanta P, Hirshman MF, Middelbeek RJW, Grove K, Goodyear LJ, Kellis M. Yang J, et al. Among authors: nigro p. Cell Metab. 2022 Oct 4;34(10):1578-1593.e6. doi: 10.1016/j.cmet.2022.09.004. Cell Metab. 2022. PMID: 36198295 Free PMC article.
Exercise training remodels inguinal white adipose tissue through adaptations in innervation, vascularization, and the extracellular matrix.
Nigro P, Vamvini M, Yang J, Caputo T, Ho LL, Carbone NP, Papadopoulos D, Conlin R, He J, Hirshman MF, White JD, Robidoux J, Hickner RC, Nielsen S, Pedersen BK, Kellis M, Middelbeek RJW, Goodyear LJ. Nigro P, et al. Cell Rep. 2023 Apr 25;42(4):112392. doi: 10.1016/j.celrep.2023.112392. Epub 2023 Apr 13. Cell Rep. 2023. PMID: 37058410 Free PMC article.
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