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A natural-product switch for a dynamic protein interface.
Scheepstra M, Nieto L, Hirsch AK, Fuchs S, Leysen S, Lam CV, in het Panhuis L, van Boeckel CA, Wienk H, Boelens R, Ottmann C, Milroy LG, Brunsveld L. Scheepstra M, et al. Among authors: nieto l. Angew Chem Int Ed Engl. 2014 Jun 16;53(25):6443-8. doi: 10.1002/anie.201403773. Epub 2014 May 12. Angew Chem Int Ed Engl. 2014. PMID: 24821627
Insights into the interaction of discodermolide and docetaxel with tubulin. Mapping the binding sites of microtubule-stabilizing agents by using an integrated NMR and computational approach.
Canales A, Rodríguez-Salarichs J, Trigili C, Nieto L, Coderch C, Andreu JM, Paterson I, Jiménez-Barbero J, Díaz JF. Canales A, et al. Among authors: nieto l. ACS Chem Biol. 2011 Aug 19;6(8):789-99. doi: 10.1021/cb200099u. Epub 2011 May 13. ACS Chem Biol. 2011. PMID: 21539341 Free article.
Heparin modulates the mitogenic activity of fibroblast growth factor by inducing dimerization of its receptor. a 3D view by using NMR.
Nieto L, Canales Á, Fernández IS, Santillana E, González-Corrochano R, Redondo-Horcajo M, Cañada FJ, Nieto P, Martín-Lomas M, Giménez-Gallego G, Jiménez-Barbero J. Nieto L, et al. Among authors: nieto p. Chembiochem. 2013 Sep 23;14(14):1732-44. doi: 10.1002/cbic.201300313. Epub 2013 Aug 12. Chembiochem. 2013. PMID: 23940086
Molecular recognition of epothilones by microtubules and tubulin dimers revealed by biochemical and NMR approaches.
Canales A, Nieto L, Rodríguez-Salarichs J, Sánchez-Murcia PA, Coderch C, Cortés-Cabrera A, Paterson I, Carlomagno T, Gago F, Andreu JM, Altmann KH, Jiménez-Barbero J, Díaz JF. Canales A, et al. Among authors: nieto l. ACS Chem Biol. 2014 Apr 18;9(4):1033-43. doi: 10.1021/cb400673h. Epub 2014 Feb 25. ACS Chem Biol. 2014. PMID: 24524625 Free article.
188 results