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MK3 modulation affects BMI1-dependent and independent cell cycle check-points.
Prickaerts P, Niessen HE, Dahlmans VE, Spaapen F, Salvaing J, Vanhove J, Geijselaers C, Bartels SJ, Partouns I, Neumann D, Speel EJ, Takihara Y, Wouters BG, Voncken JW. Prickaerts P, et al. Among authors: niessen he. PLoS One. 2015 Apr 8;10(4):e0118840. doi: 10.1371/journal.pone.0118840. eCollection 2015. PLoS One. 2015. PMID: 25853770 Free PMC article.
MK3 controls Polycomb target gene expression via negative feedback on ERK.
Prickaerts P, Niessen HE, Mouchel-Vielh E, Dahlmans VE, van den Akker GG, Geijselaers C, Adriaens ME, Spaapen F, Takihara Y, Rapp UR, Peronnet F, Voncken JW. Prickaerts P, et al. Among authors: niessen he. Epigenetics Chromatin. 2012 Aug 7;5(1):12. doi: 10.1186/1756-8935-5-12. Epigenetics Chromatin. 2012. PMID: 22870894 Free PMC article.
The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5.
Rouschop KM, van den Beucken T, Dubois L, Niessen H, Bussink J, Savelkouls K, Keulers T, Mujcic H, Landuyt W, Voncken JW, Lambin P, van der Kogel AJ, Koritzinsky M, Wouters BG. Rouschop KM, et al. J Clin Invest. 2010 Jan;120(1):127-41. doi: 10.1172/JCI40027. Epub 2009 Dec 14. J Clin Invest. 2010. PMID: 20038797 Free PMC article.
Promoter CpG island hypermethylation- and H3K9me3 and H3K27me3-mediated epigenetic silencing targets the deleted in colon cancer (DCC) gene in colorectal carcinogenesis without affecting neighboring genes on chromosomal region 18q21.
Derks S, Bosch LJ, Niessen HE, Moerkerk PT, van den Bosch SM, Carvalho B, Mongera S, Voncken JW, Meijer GA, de Bruïne AP, Herman JG, van Engeland M. Derks S, et al. Among authors: niessen he. Carcinogenesis. 2009 Jun;30(6):1041-8. doi: 10.1093/carcin/bgp073. Epub 2009 Mar 27. Carcinogenesis. 2009. PMID: 19329758
Genetics and epigenetics of cutaneous malignant melanoma: a concert out of tune.
van den Hurk K, Niessen HE, Veeck J, van den Oord JJ, van Steensel MA, Zur Hausen A, van Engeland M, Winnepenninckx VJ. van den Hurk K, et al. Among authors: niessen he. Biochim Biophys Acta. 2012 Aug;1826(1):89-102. doi: 10.1016/j.bbcan.2012.03.011. Epub 2012 Mar 31. Biochim Biophys Acta. 2012. PMID: 22503822 Review.
15 results