Niesen FH - Search Results

1

Kinase inhibitor selectivity profiling using differential scanning fluorimetry.

Fedorov O, Niesen FH, Knapp S. Fedorov O, et al. Among authors: niesen fh. Methods Mol Biol. 2012;795:109-18. doi: 10.1007/978-1-61779-337-0_7. Methods Mol Biol. 2012. PMID: 21960218

2

Potent and selective inhibitors of NAD⁺-dependent 15-hydroxyprostaglandin dehydrogenase (HPGD).

Jadhav A, Niesen FH, Schultz L, Oppermann U, Maloney DJ, Simeonov A. Jadhav A, et al. Among authors: niesen fh. 2010 Mar 4 [updated 2011 Mar 11]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. 2010 Mar 4 [updated 2011 Mar 11]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. PMID: 21735612 Free Books & Documents. Review.

3

DNA damage in oocytes induces a switch of the quality control factor TAp63α from dimer to tetramer.

Deutsch GB, Zielonka EM, Coutandin D, Weber TA, Schäfer B, Hannewald J, Luh LM, Durst FG, Ibrahim M, Hoffmann J, Niesen FH, Sentürk A, Kunkel H, Brutschy B, Schleiff E, Knapp S, Acker-Palmer A, Grez M, McKeon F, Dötsch V. Deutsch GB, et al. Among authors: niesen fh. Cell. 2011 Feb 18;144(4):566-76. doi: 10.1016/j.cell.2011.01.013. Cell. 2011. PMID: 21335238 Free PMC article.

4

High-affinity inhibitors of human NAD-dependent 15-hydroxyprostaglandin dehydrogenase: mechanisms of inhibition and structure-activity relationships.

Niesen FH, Schultz L, Jadhav A, Bhatia C, Guo K, Maloney DJ, Pilka ES, Wang M, Oppermann U, Heightman TD, Simeonov A. Niesen FH, et al. PLoS One. 2010 Nov 2;5(11):e13719. doi: 10.1371/journal.pone.0013719. PLoS One. 2010. PMID: 21072165 Free PMC article.

5

A prominent β-hairpin structure in the winged-helix domain of RECQ1 is required for DNA unwinding and oligomer formation.

Lucic B, Zhang Y, King O, Mendoza-Maldonado R, Berti M, Niesen FH, Burgess-Brown NA, Pike AC, Cooper CD, Gileadi O, Vindigni A. Lucic B, et al. Among authors: niesen fh. Nucleic Acids Res. 2011 Mar;39(5):1703-17. doi: 10.1093/nar/gkq1031. Epub 2010 Nov 8. Nucleic Acids Res. 2011. PMID: 21059676 Free PMC article.

6

Structure of the CaMKIIdelta/calmodulin complex reveals the molecular mechanism of CaMKII kinase activation.

Rellos P, Pike AC, Niesen FH, Salah E, Lee WH, von Delft F, Knapp S. Rellos P, et al. Among authors: niesen fh. PLoS Biol. 2010 Jul 27;8(7):e1000426. doi: 10.1371/journal.pbio.1000426. PLoS Biol. 2010. PMID: 20668654 Free PMC article.

7

Thermolability of mutant MMACHC protein in the vitamin B12-responsive cblC disorder.

Froese DS, Healy S, McDonald M, Kochan G, Oppermann U, Niesen FH, Gravel RA. Froese DS, et al. Among authors: niesen fh. Mol Genet Metab. 2010 May;100(1):29-36. doi: 10.1016/j.ymgme.2010.02.005. Epub 2010 Feb 15. Mol Genet Metab. 2010. PMID: 20219402 Free PMC article.

8

Structural basis for substrate specificity in human monomeric carbonyl reductases.

Pilka ES, Niesen FH, Lee WH, El-Hawari Y, Dunford JE, Kochan G, Wsol V, Martin HJ, Maser E, Oppermann U. Pilka ES, et al. Among authors: niesen fh. PLoS One. 2009 Oct 20;4(10):e7113. doi: 10.1371/journal.pone.0007113. PLoS One. 2009. PMID: 19841672 Free PMC article.

9

Conformational stability and activity of p73 require a second helix in the tetramerization domain.

Coutandin D, Löhr F, Niesen FH, Ikeya T, Weber TA, Schäfer B, Zielonka EM, Bullock AN, Yang A, Güntert P, Knapp S, McKeon F, Ou HD, Dötsch V. Coutandin D, et al. Among authors: niesen fh. Cell Death Differ. 2009 Dec;16(12):1582-9. doi: 10.1038/cdd.2009.139. Epub 2009 Sep 18. Cell Death Differ. 2009. PMID: 19763140

10

Structure of dystrophia myotonica protein kinase.

Elkins JM, Amos A, Niesen FH, Pike AC, Fedorov O, Knapp S. Elkins JM, et al. Among authors: niesen fh. Protein Sci. 2009 Apr;18(4):782-91. doi: 10.1002/pro.82. Protein Sci. 2009. PMID: 19309729 Free PMC article.

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