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Membrane transporters in drug development.
International Transporter Consortium; Giacomini KM, Huang SM, Tweedie DJ, Benet LZ, Brouwer KL, Chu X, Dahlin A, Evers R, Fischer V, Hillgren KM, Hoffmaster KA, Ishikawa T, Keppler D, Kim RB, Lee CA, Niemi M, Polli JW, Sugiyama Y, Swaan PW, Ware JA, Wright SH, Yee SW, Zamek-Gliszczynski MJ, Zhang L. International Transporter Consortium, et al. Among authors: niemi m. Nat Rev Drug Discov. 2010 Mar;9(3):215-36. doi: 10.1038/nrd3028. Nat Rev Drug Discov. 2010. PMID: 20190787 Free PMC article. Review.
The Clinical Pharmacogenetics Implementation Consortium Guideline for SLCO1B1, ABCG2, and CYP2C9 genotypes and Statin-Associated Musculoskeletal Symptoms.
Cooper-DeHoff RM, Niemi M, Ramsey LB, Luzum JA, Tarkiainen EK, Straka RJ, Gong L, Tuteja S, Wilke RA, Wadelius M, Larson EA, Roden DM, Klein TE, Yee SW, Krauss RM, Turner RM, Palaniappan L, Gaedigk A, Giacomini KM, Caudle KE, Voora D. Cooper-DeHoff RM, et al. Among authors: niemi m. Clin Pharmacol Ther. 2022 May;111(5):1007-1021. doi: 10.1002/cpt.2557. Epub 2022 Mar 11. Clin Pharmacol Ther. 2022. PMID: 35152405 Free PMC article.
Role of gemfibrozil as an inhibitor of CYP2C8 and membrane transporters.
Tornio A, Neuvonen PJ, Niemi M, Backman JT. Tornio A, et al. Among authors: niemi m. Expert Opin Drug Metab Toxicol. 2017 Jan;13(1):83-95. doi: 10.1080/17425255.2016.1227791. Epub 2016 Aug 31. Expert Opin Drug Metab Toxicol. 2017. PMID: 27548563 Review.
Cyclosporine markedly raises the plasma concentrations of repaglinide.
Kajosaari LI, Niemi M, Neuvonen M, Laitila J, Neuvonen PJ, Backman JT. Kajosaari LI, et al. Among authors: niemi m. Clin Pharmacol Ther. 2005 Oct;78(4):388-99. doi: 10.1016/j.clpt.2005.07.005. Clin Pharmacol Ther. 2005. PMID: 16198658 Clinical Trial.
Pharmacokinetics and response to pravastatin in paediatric patients with familial hypercholesterolaemia and in paediatric cardiac transplant recipients in relation to polymorphisms of the SLCO1B1 and ABCB1 genes.
Hedman M, Antikainen M, Holmberg C, Neuvonen M, Eichelbaum M, Kivistö KT, Neuvonen PJ, Niemi M. Hedman M, et al. Among authors: niemi m. Br J Clin Pharmacol. 2006 Jun;61(6):706-15. doi: 10.1111/j.1365-2125.2006.02643.x. Br J Clin Pharmacol. 2006. PMID: 16722833 Free PMC article.
546 results