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Oral supplementation of nicotinamide riboside alters intestinal microbial composition in rats and mice, but not humans.
Peluso AA, Lundgaard AT, Babaei P, Mousovich-Neto F, Rocha AL, Damgaard MV, Bak EG, Gnanasekaran T, Dollerup OL, Trammell SAJ, Nielsen TS, Kern T, Abild CB, Sulek K, Ma T, Gerhart-Hines Z, Gillum MP, Arumugam M, Ørskov C, McCloskey D, Jessen N, Herrgård MJ, Mori MAS, Treebak JT. Peluso AA, et al. Among authors: nielsen ts. NPJ Aging. 2023 Apr 3;9(1):7. doi: 10.1038/s41514-023-00106-4. NPJ Aging. 2023. PMID: 37012386 Free PMC article.
Hepatocyte-specific perturbation of NAD+ biosynthetic pathways in mice induces reversible nonalcoholic steatohepatitis-like phenotypes.
Dall M, Hassing AS, Niu L, Nielsen TS, Ingerslev LR, Sulek K, Trammell SAJ, Gillum MP, Barrès R, Larsen S, Poulsen SS, Mann M, Ørskov C, Treebak JT. Dall M, et al. Among authors: nielsen ts. J Biol Chem. 2021 Dec;297(6):101388. doi: 10.1016/j.jbc.2021.101388. Epub 2021 Nov 8. J Biol Chem. 2021. PMID: 34762911 Free PMC article.
Dietary fat drives whole-body insulin resistance and promotes intestinal inflammation independent of body weight gain.
Jensen BA, Nielsen TS, Fritzen AM, Holm JB, Fjære E, Serup AK, Borkowski K, Risis S, Pærregaard SI, Søgaard I, Poupeau A, Poulsen M, Ma T, Sina C, Kiens B, Madsen L, Kristiansen K, Treebak JT. Jensen BA, et al. Among authors: nielsen ts. Metabolism. 2016 Dec;65(12):1706-1719. doi: 10.1016/j.metabol.2016.09.002. Epub 2016 Sep 12. Metabolism. 2016. PMID: 27832859 Free article.
NAMPT-dependent NAD+ biosynthesis controls circadian metabolism in a tissue-specific manner.
Basse AL, Nielsen KN, Karavaeva I, Ingerslev LR, Ma T, Havelund JF, Nielsen TS, Frost M, Peics J, Dalbram E, Dall M, Zierath JR, Barrès R, Færgeman NJ, Treebak JT, Gerhart-Hines Z. Basse AL, et al. Among authors: nielsen ts, nielsen kn. Proc Natl Acad Sci U S A. 2023 Apr 4;120(14):e2220102120. doi: 10.1073/pnas.2220102120. Epub 2023 Mar 30. Proc Natl Acad Sci U S A. 2023. PMID: 36996103 Free PMC article.
Skeletal muscle O-GlcNAc transferase is important for muscle energy homeostasis and whole-body insulin sensitivity.
Shi H, Munk A, Nielsen TS, Daughtry MR, Larsson L, Li S, Høyer KF, Geisler HW, Sulek K, Kjøbsted R, Fisher T, Andersen MM, Shen Z, Hansen UK, England EM, Cheng Z, Højlund K, Wojtaszewski JFP, Yang X, Hulver MW, Helm RF, Treebak JT, Gerrard DE. Shi H, et al. Among authors: nielsen ts. Mol Metab. 2018 May;11:160-177. doi: 10.1016/j.molmet.2018.02.010. Epub 2018 Feb 24. Mol Metab. 2018. PMID: 29525407 Free PMC article.
104 results