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ASPSCR1-TFE3 reprograms transcription by organizing enhancer loops around hexameric VCP/p97.
Pozner A, Li L, Verma SP, Wang S, Barrott JJ, Nelson ML, Yu JSE, Negri GL, Colborne S, Hughes CS, Zhu JF, Lambert SL, Carroll LS, Smith-Fry K, Stewart MG, Kannan S, Jensen B, John CM, Sikdar S, Liu H, Dang NH, Bourdage J, Li J, Vahrenkamp JM, Mortenson KL, Groundland JS, Wustrack R, Senger DL, Zemp FJ, Mahoney DJ, Gertz J, Zhang X, Lazar AJ, Hirst M, Morin GB, Nielsen TO, Shen PS, Jones KB. Pozner A, et al. Among authors: nielsen to. Nat Commun. 2024 Feb 7;15(1):1165. doi: 10.1038/s41467-024-45280-5. Nat Commun. 2024. PMID: 38326311 Free PMC article.
The FUS-DDIT3 Interactome in Myxoid Liposarcoma.
Yu JSE, Colborne S, Hughes CS, Morin GB, Nielsen TO. Yu JSE, et al. Among authors: nielsen to. Neoplasia. 2019 Aug;21(8):740-751. doi: 10.1016/j.neo.2019.05.004. Epub 2019 Jun 17. Neoplasia. 2019. PMID: 31220736 Free PMC article.
The epigenomics of sarcoma.
Nacev BA, Jones KB, Intlekofer AM, Yu JSE, Allis CD, Tap WD, Ladanyi M, Nielsen TO. Nacev BA, et al. Among authors: nielsen to. Nat Rev Cancer. 2020 Oct;20(10):608-623. doi: 10.1038/s41568-020-0288-4. Epub 2020 Aug 11. Nat Rev Cancer. 2020. PMID: 32782366 Free PMC article. Review.
Death by HDAC Inhibition in Synovial Sarcoma Cells.
Laporte AN, Poulin NM, Barrott JJ, Wang XQ, Lorzadeh A, Vander Werff R, Jones KB, Underhill TM, Nielsen TO. Laporte AN, et al. Among authors: nielsen to. Mol Cancer Ther. 2017 Dec;16(12):2656-2667. doi: 10.1158/1535-7163.MCT-17-0397. Epub 2017 Sep 6. Mol Cancer Ther. 2017. PMID: 28878027
Establishment and characterization of a new human myxoid liposarcoma cell line (DL-221) with the FUS-DDIT3 translocation.
de Graaff MA, Yu JS, Beird HC, Ingram DR, Nguyen T, Juehui Liu J, Bolshakov S, Szuhai K, Åman P, Torres KE, Lev D, Nielsen TO, Bovée JV, Lazar AJ, Somaiah N. de Graaff MA, et al. Among authors: nielsen to. Lab Invest. 2016 Aug;96(8):885-94. doi: 10.1038/labinvest.2016.64. Epub 2016 Jun 6. Lab Invest. 2016. PMID: 27270875 Free PMC article.
The SS18-SSX Oncoprotein Hijacks KDM2B-PRC1.1 to Drive Synovial Sarcoma.
Banito A, Li X, Laporte AN, Roe JS, Sanchez-Vega F, Huang CH, Dancsok AR, Hatzi K, Chen CC, Tschaharganeh DF, Chandwani R, Tasdemir N, Jones KB, Capecchi MR, Vakoc CR, Schultz N, Ladanyi M, Nielsen TO, Lowe SW. Banito A, et al. Among authors: nielsen to. Cancer Cell. 2018 Mar 12;33(3):527-541.e8. doi: 10.1016/j.ccell.2018.01.018. Epub 2018 Mar 1. Cancer Cell. 2018. PMID: 29502955 Free PMC article.
232 results