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CTSH regulates β-cell function and disease progression in newly diagnosed type 1 diabetes patients.
Fløyel T, Brorsson C, Nielsen LB, Miani M, Bang-Berthelsen CH, Friedrichsen M, Overgaard AJ, Berchtold LA, Wiberg A, Poulsen P, Hansen L, Rosinger S, Boehm BO, Ram R, Nguyen Q, Mehta M, Morahan G, Concannon P, Bergholdt R, Nielsen JH, Reinheckel T, von Herrath M, Vaag A, Eizirik DL, Mortensen HB, Størling J, Pociot F. Fløyel T, et al. Among authors: nielsen jh, nielsen lb. Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):10305-10. doi: 10.1073/pnas.1402571111. Epub 2014 Jun 30. Proc Natl Acad Sci U S A. 2014. PMID: 24982147 Free PMC article. Clinical Trial.
Relationship between ZnT8Ab, the SLC30A8 gene and disease progression in children with newly diagnosed type 1 diabetes.
Nielsen LB, Vaziri-Sani F, Pörksen S, Andersen ML, Svensson J, Bergholdt R, Pociot F, Hougaard P, de Beaufort C, Castaño L, Mortensen HB, Lernmark A, Hansen L; Hvidoere Study Group on Childhood Diabetes. Nielsen LB, et al. Autoimmunity. 2011 Dec;44(8):616-23. doi: 10.3109/08916934.2011.576724. Epub 2011 May 23. Autoimmunity. 2011. PMID: 21604969
Circulating levels of microRNA from children with newly diagnosed type 1 diabetes and healthy controls: evidence that miR-25 associates to residual beta-cell function and glycaemic control during disease progression.
Nielsen LB, Wang C, Sørensen K, Bang-Berthelsen CH, Hansen L, Andersen ML, Hougaard P, Juul A, Zhang CY, Pociot F, Mortensen HB. Nielsen LB, et al. Exp Diabetes Res. 2012;2012:896362. doi: 10.1155/2012/896362. Epub 2012 Jul 5. Exp Diabetes Res. 2012. PMID: 22829805 Free PMC article.
Genetic Risk Score Modelling for Disease Progression in New-Onset Type 1 Diabetes Patients: Increased Genetic Load of Islet-Expressed and Cytokine-Regulated Candidate Genes Predicts Poorer Glycemic Control.
Brorsson CA, Nielsen LB, Andersen ML, Kaur S, Bergholdt R, Hansen L, Mortensen HB, Pociot F, Størling J; Hvidoere Study Group On Childhood Diabetes. Brorsson CA, et al. Among authors: nielsen lb. J Diabetes Res. 2016;2016:9570424. doi: 10.1155/2016/9570424. Epub 2016 Jan 20. J Diabetes Res. 2016. PMID: 26904692 Free PMC article.
Complex multi-block analysis identifies new immunologic and genetic disease progression patterns associated with the residual β-cell function 1 year after diagnosis of type 1 diabetes.
Andersen ML, Rasmussen MA, Pörksen S, Svensson J, Vikre-Jørgensen J, Thomsen J, Hertel NT, Johannesen J, Pociot F, Petersen JS, Hansen L, Mortensen HB, Nielsen LB. Andersen ML, et al. Among authors: nielsen lb. PLoS One. 2013 Jun 5;8(6):e64632. doi: 10.1371/journal.pone.0064632. Print 2013. PLoS One. 2013. PMID: 23755131 Free PMC article.
Variation within the PPARG gene is associated with residual beta-cell function and glycemic control in children and adolescents during the first year of clinical type 1 diabetes.
Pörksen S, Nielsen LB, Mortensen HB, Danne T, Kocova M, Castaño L, Pociot F, Hougaard P, Ekstrøm CT, Gammeltoft S, Knip M, Hansen L; Hvidøre Study Group on Childhood Diabetes. Pörksen S, et al. Among authors: nielsen lb. Pediatr Diabetes. 2008 Jul 28;9(4 Pt 1):297-302. doi: 10.1111/j.1399-5448.2008.00398.x. Epub 2008 May 7. Pediatr Diabetes. 2008. PMID: 18466209
Disease progression among 446 children with newly diagnosed type 1 diabetes located in Scandinavia, Europe, and North America during the last 27 yr.
Max Andersen ML, Nielsen LB, Svensson J, Pörksen S, Hougaard P, Beam C, Greenbaum C, Becker D, Petersen JS, Hansen L, Mortensen HB. Max Andersen ML, et al. Among authors: nielsen lb. Pediatr Diabetes. 2014 Aug;15(5):345-54. doi: 10.1111/pedi.12098. Epub 2013 Nov 25. Pediatr Diabetes. 2014. PMID: 24731251
Polymorphisms in the CTSH gene may influence the progression of diabetic retinopathy: a candidate-gene study in the Danish Cohort of Pediatric Diabetes 1987 (DCPD1987).
Thorsen SU, Sandahl K, Nielsen LB, Broe R, Rasmussen ML, Peto T, Grauslund J, Andersen ML, Mortensen HB, Pociot F, Olsen BS, Brorsson C. Thorsen SU, et al. Among authors: nielsen lb. Graefes Arch Clin Exp Ophthalmol. 2015 Nov;253(11):1959-65. doi: 10.1007/s00417-015-3118-8. Epub 2015 Aug 6. Graefes Arch Clin Exp Ophthalmol. 2015. PMID: 26245339
A20 Inhibits β-Cell Apoptosis by Multiple Mechanisms and Predicts Residual β-Cell Function in Type 1 Diabetes.
Fukaya M, Brorsson CA, Meyerovich K, Catrysse L, Delaroche D, Vanzela EC, Ortis F, Beyaert R, Nielsen LB, Andersen ML, Mortensen HB, Pociot F, van Loo G, Størling J, Cardozo AK. Fukaya M, et al. Among authors: nielsen lb. Mol Endocrinol. 2016 Jan;30(1):48-61. doi: 10.1210/me.2015-1176. Epub 2015 Dec 10. Mol Endocrinol. 2016. PMID: 26652732 Free PMC article.
271 results