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A proteomics analysis of 5xFAD mouse brain regions reveals the lysosome-associated protein Arl8b as a candidate biomarker for Alzheimer's disease.
Boeddrich A, Haenig C, Neuendorf N, Blanc E, Ivanov A, Kirchner M, Schleumann P, Bayraktaroğlu I, Richter M, Molenda CM, Sporbert A, Zenkner M, Schnoegl S, Suenkel C, Schneider LS, Rybak-Wolf A, Kochnowsky B, Byrne LM, Wild EJ, Nielsen JE, Dittmar G, Peters O, Beule D, Wanker EE. Boeddrich A, et al. Among authors: nielsen je. Genome Med. 2023 Jul 20;15(1):50. doi: 10.1186/s13073-023-01206-2. Genome Med. 2023. PMID: 37468900 Free PMC article.
Endo-lysosomal protein concentrations in CSF from patients with frontotemporal dementia caused by CHMP2B mutation.
Toft A, Sjödin S, Simonsen AH, Ejlerskov P, Roos P, Musaeus CS, Henriksen EE, Nielsen TT, Brinkmalm A, Blennow K, Zetterberg H, Nielsen JE. Toft A, et al. Among authors: nielsen tt, nielsen je. Alzheimers Dement (Amst). 2023 Feb 16;15(1):e12402. doi: 10.1002/dad2.12402. eCollection 2023 Jan-Mar. Alzheimers Dement (Amst). 2023. PMID: 36815874 Free PMC article.
Defining active progressive multiple sclerosis.
Sellebjerg F, Börnsen L, Ammitzbøll C, Nielsen JE, Vinther-Jensen T, Hjermind LE, von Essen M, Ratzer RL, Soelberg Sørensen P, Romme Christensen J. Sellebjerg F, et al. Among authors: nielsen je. Mult Scler. 2017 Nov;23(13):1727-1735. doi: 10.1177/1352458517726592. Epub 2017 Aug 23. Mult Scler. 2017. PMID: 28831853
Frontotemporal dementia caused by CHMP2B mutation is characterised by neuronal lysosomal storage pathology.
Clayton EL, Mizielinska S, Edgar JR, Nielsen TT, Marshall S, Norona FE, Robbins M, Damirji H, Holm IE, Johannsen P, Nielsen JE, Asante EA, Collinge J; FReJA consortium; Isaacs AM. Clayton EL, et al. Among authors: nielsen tt, nielsen je. Acta Neuropathol. 2015 Oct;130(4):511-23. doi: 10.1007/s00401-015-1475-3. Epub 2015 Sep 10. Acta Neuropathol. 2015. PMID: 26358247 Free PMC article.
Golgi fragmentation - One of the earliest organelle phenotypes in Alzheimer's disease neurons.
Haukedal H, Corsi GI, Gadekar VP, Doncheva NT, Kedia S, de Haan N, Chandrasekaran A, Jensen P, Schiønning P, Vallin S, Marlet FR, Poon A, Pires C, Agha FK, Wandall HH, Cirera S, Simonsen AH, Nielsen TT, Nielsen JE, Hyttel P, Muddashetty R, Aldana BI, Gorodkin J, Nair D, Meyer M, Larsen MR, Freude K. Haukedal H, et al. Among authors: nielsen tt, nielsen je. Front Neurosci. 2023 Feb 16;17:1120086. doi: 10.3389/fnins.2023.1120086. eCollection 2023. Front Neurosci. 2023. PMID: 36875643 Free PMC article.
Early Intrathecal T Helper 17.1 Cell Activity in Huntington Disease.
von Essen MR, Hellem MNN, Vinther-Jensen T, Ammitzbøll C, Hansen RH, Hjermind LE, Nielsen TT, Nielsen JE, Sellebjerg F. von Essen MR, et al. Among authors: nielsen tt, nielsen je. Ann Neurol. 2020 Feb;87(2):246-255. doi: 10.1002/ana.25647. Epub 2019 Nov 27. Ann Neurol. 2020. PMID: 31725947
Peripheral helper T cells in the pathogenesis of multiple sclerosis.
Holm Hansen R, Højsgaard Chow H, Talbot J, Buhelt S, Nickelsen Hellem MN, Nielsen JE, Sellebjerg FT, von Essen MR. Holm Hansen R, et al. Among authors: nielsen je. Mult Scler. 2022 Aug;28(9):1340-1350. doi: 10.1177/13524585211067696. Epub 2022 Feb 3. Mult Scler. 2022. PMID: 35112578
456 results