Nielsen AT - Search Results

1

Synergistic stabilization of a double mutant in chymotrypsin inhibitor 2 from a library screen in E. coli.

Hamborg L, Granata D, Olsen JG, Roche JV, Pedersen LE, Nielsen AT, Lindorff-Larsen K, Teilum K. Hamborg L, et al. Among authors: nielsen at. Commun Biol. 2021 Aug 18;4(1):980. doi: 10.1038/s42003-021-02490-7. Commun Biol. 2021. PMID: 34408246 Free PMC article.

2

Accelerating genome editing in CHO cells using CRISPR Cas9 and CRISPy, a web-based target finding tool.

Ronda C, Pedersen LE, Hansen HG, Kallehauge TB, Betenbaugh MJ, Nielsen AT, Kildegaard HF. Ronda C, et al. Among authors: nielsen at. Biotechnol Bioeng. 2014 Aug;111(8):1604-16. doi: 10.1002/bit.25233. Epub 2014 May 22. Biotechnol Bioeng. 2014. PMID: 24827782 Free PMC article.

3

CRMAGE: CRISPR Optimized MAGE Recombineering.

Ronda C, Pedersen LE, Sommer MO, Nielsen AT. Ronda C, et al. Among authors: nielsen at. Sci Rep. 2016 Jan 22;6:19452. doi: 10.1038/srep19452. Sci Rep. 2016. PMID: 26797514 Free PMC article.

4

Multiplex Genome Editing in Escherichia coli.

Jensen SI, Nielsen AT. Jensen SI, et al. Among authors: nielsen at. Methods Mol Biol. 2018;1671:119-129. doi: 10.1007/978-1-4939-7295-1_8. Methods Mol Biol. 2018. PMID: 29170956

5

Genome-wide systematic identification of methyltransferase recognition and modification patterns.

Jensen TØ, Tellgren-Roth C, Redl S, Maury J, Jacobsen SAB, Pedersen LE, Nielsen AT. Jensen TØ, et al. Among authors: nielsen at. Nat Commun. 2019 Aug 19;10(1):3311. doi: 10.1038/s41467-019-11179-9. Nat Commun. 2019. PMID: 31427571 Free PMC article.

6

Genome-Wide CRISPRi-Based Identification of Targets for Decoupling Growth from Production.

Li S, Jendresen CB, Landberg J, Pedersen LE, Sonnenschein N, Jensen SI, Nielsen AT. Li S, et al. Among authors: nielsen at. ACS Synth Biol. 2020 May 15;9(5):1030-1040. doi: 10.1021/acssynbio.9b00143. Epub 2020 Apr 21. ACS Synth Biol. 2020. PMID: 32268068

7

A dual-reporter system for investigating and optimizing protein translation and folding in E. coli.

Zutz A, Hamborg L, Pedersen LE, Kassem MM, Papaleo E, Koza A, Herrgård MJ, Jensen SI, Teilum K, Lindorff-Larsen K, Nielsen AT. Zutz A, et al. Among authors: nielsen at. Nat Commun. 2021 Oct 19;12(1):6093. doi: 10.1038/s41467-021-26337-1. Nat Commun. 2021. PMID: 34667164 Free PMC article.

8

Folding of heterologous proteins in bacterial cell factories: Cellular mechanisms and engineering strategies.

Rong Y, Jensen SI, Lindorff-Larsen K, Nielsen AT. Rong Y, et al. Among authors: nielsen at. Biotechnol Adv. 2023 Mar-Apr;63:108079. doi: 10.1016/j.biotechadv.2022.108079. Epub 2022 Dec 14. Biotechnol Adv. 2023. PMID: 36528238 Review.

9

Laboratory evolution reveals general and specific tolerance mechanisms for commodity chemicals.

Lennen RM, Lim HG, Jensen K, Mohammed ET, Phaneuf PV, Noh MH, Malla S, Börner RA, Chekina K, Özdemir E, Bonde I, Koza A, Maury J, Pedersen LE, Schöning LY, Sonnenschein N, Palsson BO, Nielsen AT, Sommer MOA, Herrgård MJ, Feist AM. Lennen RM, et al. Among authors: nielsen at. Metab Eng. 2023 Mar;76:179-192. doi: 10.1016/j.ymben.2023.01.012. Epub 2023 Feb 3. Metab Eng. 2023. PMID: 36738854 Free article.

10

Engineering of high yield production of L-serine in Escherichia coli.

Mundhada H, Schneider K, Christensen HB, Nielsen AT. Mundhada H, et al. Among authors: nielsen at. Biotechnol Bioeng. 2016 Apr;113(4):807-16. doi: 10.1002/bit.25844. Epub 2015 Oct 7. Biotechnol Bioeng. 2016. PMID: 26416585

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