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Large Libraries of Structurally Diverse Macrocycles Suitable for Membrane Permeation.
Nielsen AL, Bognar Z, Mothukuri GK, Zarda A, Schuttel M, Merz ML, Ji X, Will E, Chinellato M, Bartling CRO, Stromgaard K, Cendron L, Angelini A, Heinis C. Nielsen AL, et al. Angew Chem Int Ed Engl. 2024 Apr 11:e202400350. doi: 10.1002/anie.202400350. Online ahead of print. Angew Chem Int Ed Engl. 2024. PMID: 38602024
Solid-phase peptide synthesis in 384-well plates.
Schüttel M, Will E, Sangouard G, Zarda A, Habeshian S, Nielsen AL, Heinis C. Schüttel M, et al. Among authors: nielsen al. J Pept Sci. 2024 Apr;30(4):e3555. doi: 10.1002/psc.3555. Epub 2024 Jan 14. J Pept Sci. 2024. PMID: 38220145
De novo development of small cyclic peptides that are orally bioavailable.
Merz ML, Habeshian S, Li B, David JGL, Nielsen AL, Ji X, Il Khwildy K, Duany Benitez MM, Phothirath P, Heinis C. Merz ML, et al. Among authors: nielsen al. Nat Chem Biol. 2024 May;20(5):624-633. doi: 10.1038/s41589-023-01496-y. Epub 2023 Dec 28. Nat Chem Biol. 2024. PMID: 38155304 Free PMC article.
336 results