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Kupffer cell-like syncytia replenish resident macrophage function in the fibrotic liver.
Peiseler M, Araujo David B, Zindel J, Surewaard BGJ, Lee WY, Heymann F, Nusse Y, Castanheira FVS, Shim R, Guillot A, Bruneau A, Atif J, Perciani C, Ohland C, Ganguli Mukherjee P, Niehrs A, Thuenauer R, Altfeld M, Amrein M, Liu Z, Gordon PMK, McCoy K, Deniset J, MacParland S, Ginhoux F, Tacke F, Kubes P. Peiseler M, et al. Among authors: niehrs a. Science. 2023 Sep 8;381(6662):eabq5202. doi: 10.1126/science.abq5202. Epub 2023 Sep 8. Science. 2023. PMID: 37676943
Regulation of NK-Cell Function by HLA Class II.
Niehrs A, Altfeld M. Niehrs A, et al. Front Cell Infect Microbiol. 2020 Feb 18;10:55. doi: 10.3389/fcimb.2020.00055. eCollection 2020. Front Cell Infect Microbiol. 2020. PMID: 32133304 Free PMC article.
CD49a Expression Identifies a Subset of Intrahepatic Macrophages in Humans.
Martrus G, Goebels H, Langeneckert AE, Kah J, Flomm F, Ziegler AE, Niehrs A, Löbl SM, Russu K, Hess LU, Salzberger W, Poch T, Nashan B, Schramm C, Oldhafer KJ, Dandri M, Koch M, Lunemann S, Altfeld M. Martrus G, et al. Among authors: niehrs a. Front Immunol. 2019 Jun 7;10:1247. doi: 10.3389/fimmu.2019.01247. eCollection 2019. Front Immunol. 2019. PMID: 31231382 Free PMC article.
KIR3DS1 directs NK cell-mediated protection against human adenovirus infections.
Jung JM, Ching W, Baumdick ME, Hofmann-Sieber H, Bosse JB, Koyro T, Möller KJ, Wegner L, Niehrs A, Russu K, Ohms M, Zhang W, Ehrhardt A, Duisters K, Spierings E, Hölzemer A, Körner C, Jansen SA, Peine S, Königs I, Lütgehetmann M, Perez D, Reinshagen K, Lindemans CA, Altfeld M, Belderbos M, Dobner T, Bunders MJ. Jung JM, et al. Among authors: niehrs a. Sci Immunol. 2021 Sep 17;6(63):eabe2942. doi: 10.1126/sciimmunol.abe2942. Epub 2021 Sep 17. Sci Immunol. 2021. PMID: 34533978
Engagement of TRAIL triggers degranulation and IFNγ production in human natural killer cells.
Höfle J, Trenkner T, Kleist N, Schwane V, Vollmers S, Barcelona B, Niehrs A, Fittje P, Huynh-Tran VH, Sauter J, Schmidt AH, Peine S, Hoelzemer A, Richert L, Altfeld M, Körner C. Höfle J, et al. Among authors: niehrs a. EMBO Rep. 2022 Aug 3;23(8):e54133. doi: 10.15252/embr.202154133. Epub 2022 Jun 27. EMBO Rep. 2022. PMID: 35758160 Free PMC article.
The co-inhibitory receptor TIGIT regulates NK cell function and is upregulated in human intrahepatic CD56bright NK cells.
Ziegler AE, Fittje P, Müller LM, Ahrenstorf AE, Hagemann K, Hagen SH, Hess LU, Niehrs A, Poch T, Ravichandran G, Löbl SM, Padoan B, Brias S, Hennesen J, Richard M, Richert L, Peine S, Oldhafer KJ, Fischer L, Schramm C, Martrus G, Bunders MJ, Altfeld M, Lunemann S. Ziegler AE, et al. Among authors: niehrs a. Front Immunol. 2023 Feb 9;14:1117320. doi: 10.3389/fimmu.2023.1117320. eCollection 2023. Front Immunol. 2023. PMID: 36845105 Free PMC article.
A subset of HLA-DP molecules serve as ligands for the natural cytotoxicity receptor NKp44.
Niehrs A, Garcia-Beltran WF, Norman PJ, Watson GM, Hölzemer A, Chapel A, Richert L, Pommerening-Röser A, Körner C, Ozawa M, Martrus G, Rossjohn J, Lee JH, Berry R, Carrington M, Altfeld M. Niehrs A, et al. Nat Immunol. 2019 Sep;20(9):1129-1137. doi: 10.1038/s41590-019-0448-4. Epub 2019 Jul 29. Nat Immunol. 2019. PMID: 31358998 Free PMC article.
Primary HIV-1 Strains Use Nef To Downmodulate HLA-E Surface Expression.
van Stigt Thans T, Akko JI, Niehrs A, Garcia-Beltran WF, Richert L, Stürzel CM, Ford CT, Li H, Ochsenbauer C, Kappes JC, Hahn BH, Kirchhoff F, Martrus G, Sauter D, Altfeld M, Hölzemer A. van Stigt Thans T, et al. Among authors: niehrs a. J Virol. 2019 Sep 30;93(20):e00719-19. doi: 10.1128/JVI.00719-19. Print 2019 Oct 15. J Virol. 2019. PMID: 31375574 Free PMC article.
14 results