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Mesenchymal stem cell-derived extracellular vesicles reduce senescence and extend health span in mouse models of aging.
Dorronsoro A, Santiago FE, Grassi D, Zhang T, Lai RC, McGowan SJ, Angelini L, Lavasani M, Corbo L, Lu A, Brooks RW, Garcia-Contreras M, Stolz DB, Amelio A, Boregowda SV, Fallahi M, Reich A, Ricordi C, Phinney DG, Huard J, Lim SK, Niedernhofer LJ, Robbins PD. Dorronsoro A, et al. Among authors: niedernhofer lj. Aging Cell. 2021 Apr;20(4):e13337. doi: 10.1111/acel.13337. Epub 2021 Mar 16. Aging Cell. 2021. PMID: 33728821 Free PMC article.
Accelerated aging of intervertebral discs in a mouse model of progeria.
Vo N, Seo HY, Robinson A, Sowa G, Bentley D, Taylor L, Studer R, Usas A, Huard J, Alber S, Watkins SC, Lee J, Coehlo P, Wang D, Loppini M, Robbins PD, Niedernhofer LJ, Kang J. Vo N, et al. Among authors: niedernhofer lj. J Orthop Res. 2010 Dec;28(12):1600-7. doi: 10.1002/jor.21153. J Orthop Res. 2010. PMID: 20973062 Free PMC article.
Premature aging-related peripheral neuropathy in a mouse model of progeria.
Goss JR, Stolz DB, Robinson AR, Zhang M, Arbujas N, Robbins PD, Glorioso JC, Niedernhofer LJ. Goss JR, et al. Among authors: niedernhofer lj. Mech Ageing Dev. 2011 Aug;132(8-9):437-42. doi: 10.1016/j.mad.2011.04.010. Epub 2011 May 11. Mech Ageing Dev. 2011. PMID: 21596054 Free PMC article.
A mouse model of accelerated liver aging caused by a defect in DNA repair.
Gregg SQ, Gutiérrez V, Robinson AR, Woodell T, Nakao A, Ross MA, Michalopoulos GK, Rigatti L, Rothermel CE, Kamileri I, Garinis GA, Stolz DB, Niedernhofer LJ. Gregg SQ, et al. Among authors: niedernhofer lj. Hepatology. 2012 Feb;55(2):609-21. doi: 10.1002/hep.24713. Hepatology. 2012. PMID: 21953681 Free PMC article.
NF-κB negatively impacts the myogenic potential of muscle-derived stem cells.
Lu A, Proto JD, Guo L, Tang Y, Lavasani M, Tilstra JS, Niedernhofer LJ, Wang B, Guttridge DC, Robbins PD, Huard J. Lu A, et al. Among authors: niedernhofer lj. Mol Ther. 2012 Mar;20(3):661-8. doi: 10.1038/mt.2011.261. Epub 2011 Dec 13. Mol Ther. 2012. PMID: 22158056 Free PMC article.
ISSLS prize winner: inhibition of NF-κB activity ameliorates age-associated disc degeneration in a mouse model of accelerated aging.
Nasto LA, Seo HY, Robinson AR, Tilstra JS, Clauson CL, Sowa GA, Ngo K, Dong Q, Pola E, Lee JY, Niedernhofer LJ, Kang JD, Robbins PD, Vo NV. Nasto LA, et al. Among authors: niedernhofer lj. Spine (Phila Pa 1976). 2012 Oct 1;37(21):1819-25. doi: 10.1097/BRS.0b013e31824ee8f7. Spine (Phila Pa 1976). 2012. PMID: 22343279 Free PMC article.
NF-κB in Aging and Disease.
Tilstra JS, Clauson CL, Niedernhofer LJ, Robbins PD. Tilstra JS, et al. Among authors: niedernhofer lj. Aging Dis. 2011 Dec;2(6):449-65. Epub 2011 Dec 2. Aging Dis. 2011. PMID: 22396894 Free PMC article.
182 results