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Body-wide gene therapy of Duchenne muscular dystrophy in the mdx mouse model.
Denti MA, Rosa A, D'Antona G, Sthandier O, De Angelis FG, Nicoletti C, Allocca M, Pansarasa O, Parente V, Musarò A, Auricchio A, Bottinelli R, Bozzoni I. Denti MA, et al. Among authors: nicoletti c. Proc Natl Acad Sci U S A. 2006 Mar 7;103(10):3758-63. doi: 10.1073/pnas.0508917103. Epub 2006 Feb 24. Proc Natl Acad Sci U S A. 2006. PMID: 16501048 Free PMC article.
Chimeric adeno-associated virus/antisense U1 small nuclear RNA effectively rescues dystrophin synthesis and muscle function by local treatment of mdx mice.
Denti MA, Rosa A, D'Antona G, Sthandier O, De Angelis FG, Nicoletti C, Allocca M, Pansarasa O, Parente V, Musarò A, Auricchio A, Bottinelli R, Bozzoni I. Denti MA, et al. Among authors: nicoletti c. Hum Gene Ther. 2006 May;17(5):565-74. doi: 10.1089/hum.2006.17.565. Hum Gene Ther. 2006. PMID: 16716113
Skeletal muscle is a primary target of SOD1G93A-mediated toxicity.
Dobrowolny G, Aucello M, Rizzuto E, Beccafico S, Mammucari C, Boncompagni S, Belia S, Wannenes F, Nicoletti C, Del Prete Z, Rosenthal N, Molinaro M, Protasi F, Fanò G, Sandri M, Musarò A. Dobrowolny G, et al. Among authors: nicoletti c. Cell Metab. 2008 Nov;8(5):425-36. doi: 10.1016/j.cmet.2008.09.002. Cell Metab. 2008. PMID: 19046573 Free article.
MicroRNAs involved in molecular circuitries relevant for the Duchenne muscular dystrophy pathogenesis are controlled by the dystrophin/nNOS pathway.
Cacchiarelli D, Martone J, Girardi E, Cesana M, Incitti T, Morlando M, Nicoletti C, Santini T, Sthandier O, Barberi L, Auricchio A, Musarò A, Bozzoni I. Cacchiarelli D, et al. Among authors: nicoletti c. Cell Metab. 2010 Oct 6;12(4):341-351. doi: 10.1016/j.cmet.2010.07.008. Epub 2010 Aug 19. Cell Metab. 2010. PMID: 20727829 Free article.
Proliferation of Multiple Cell Types in the Skeletal Muscle Tissue Elicited by Acute p21 Suppression.
Biferi MG, Nicoletti C, Falcone G, Puggioni EMR, Passaro N, Mazzola A, Pajalunga D, Zaccagnini G, Rizzuto E, Auricchio A, Zentilin L, De Luca G, Giacca M, Martelli F, Musio A, Musarò A, Crescenzi M. Biferi MG, et al. Among authors: nicoletti c. Mol Ther. 2015 May;23(5):885-895. doi: 10.1038/mt.2015.27. Epub 2015 Feb 11. Mol Ther. 2015. PMID: 25669433 Free PMC article.
332 results