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Antiviral potential of diminazene aceturate against SARS-CoV-2 proteases using computational and in vitro approaches.
Santos ES, Silva PC, Sousa PSA, Aquino CC, Pacheco G, Teixeira LFLS, Araujo AR, Sousa FBM, Barros RO, Ramos RM, Rocha JA, Nicolau LAD, Medeiros JVR. Santos ES, et al. Among authors: nicolau lad. Chem Biol Interact. 2022 Nov 1;367:110161. doi: 10.1016/j.cbi.2022.110161. Epub 2022 Sep 15. Chem Biol Interact. 2022. PMID: 36116513 Free PMC article.
Evaluation of anti-inflammatory potential of aqueous extract and polysaccharide fraction of Thuja occidentalis Linn. in mice.
Silva IS, Nicolau LAD, Sousa FBM, Araújo S, Oliveira AP, Araújo TSL, Souza LKM, Martins CS, Aquino PEA, Carvalho LL, Silva RO, Rolim-Neto PJ, Medeiros JVR. Silva IS, et al. Among authors: nicolau lad. Int J Biol Macromol. 2017 Dec;105(Pt 1):1105-1116. doi: 10.1016/j.ijbiomac.2017.07.142. Epub 2017 Jul 24. Int J Biol Macromol. 2017. PMID: 28751047
H2S is a key antisecretory molecule against cholera toxin-induced diarrhoea in mice: Evidence for non-involvement of the AC/cAMP/PKA pathway and AMPK.
Sousa FBM, Souza LKM, Sousa NA, Araújo TSL, de Araújo S, Pacífico DM, Silva IS, Silva RO, Nicolau LAD, Souza FM, Filgueiras MC, Oliveira JS, Souza MHLP, Medeiros JVR. Sousa FBM, et al. Among authors: nicolau lad. Nitric Oxide. 2018 Jun 1;76:152-163. doi: 10.1016/j.niox.2017.09.007. Epub 2017 Sep 22. Nitric Oxide. 2018. PMID: 28943473
Topical protection of mice laryngeal mucosa using the natural product cashew gum.
Figueiredo AA, Santana APM, Nicolau LAD, Batista-Lima FJ, Wong DVT, Lucetti LT, Batista GLP, Caminha NA, Medeiros JVR, Silva DA, Leite JRSA, Santos AA, Soares PMG, Sifrim D, Souza MHLP. Figueiredo AA, et al. Among authors: nicolau lad. Laryngoscope. 2018 May;128(5):1157-1162. doi: 10.1002/lary.26958. Epub 2017 Oct 27. Laryngoscope. 2018. PMID: 29076531
Efficacy of a phenol derivative, isopropyl vanillate, as an anti-inflammatory agent: A new small molecule inhibitor of COX and neutrophil migration.
Nogueira KM, de Souza LKM, de Oliveira AP, Pacheco G, Iles B, Alencar MS, Nicolau LAD, Silva RO, da Nóbrega FR, Sousa DP, de Souza MHLP, Medeiros JVR. Nogueira KM, et al. Among authors: nicolau lad. Drug Dev Res. 2019 Aug;80(5):666-679. doi: 10.1002/ddr.21546. Epub 2019 May 21. Drug Dev Res. 2019. PMID: 31112325
Cashew gum, a biopolymer, topically protects oesophageal mucosa in non erosive reflux disease: A promising translational study.
Nicolau LAD, Batista-Lima FJ, Santana APM, Sales TMAL, Carmo-Neto JP, Freitas GB, Oliveira TM, Medeiros JVR, Silva DA, Lee C, Woodland PJ, Soares PMG, Vale ML, Santos AA, Sifrim D, Souza MHLP. Nicolau LAD, et al. Carbohydr Polym. 2019 Dec 15;226:115205. doi: 10.1016/j.carbpol.2019.115205. Epub 2019 Aug 15. Carbohydr Polym. 2019. PMID: 31582062
Biopolymer Extracted from Anadenanthera colubrina (Red Angico Gum) Exerts Therapeutic Potential in Mice: Antidiarrheal Activity and Safety Assessment.
Araújo TSL, de Oliveira TM, de Sousa NA, Souza LKM, Sousa FBM, de Oliveira AP, Nicolau LAD, da Silva AAV, Araújo AR, Magalhães PJC, Vasconcelos DFP, de Jonge HR, Souza MHLP, Silva DA, Paula RCM, Medeiros JVR. Araújo TSL, et al. Among authors: nicolau lad. Pharmaceuticals (Basel). 2020 Jan 18;13(1):17. doi: 10.3390/ph13010017. Pharmaceuticals (Basel). 2020. PMID: 31963683 Free PMC article.
45 results