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Evaluating opportunities for advancing the use of alternative methods in risk assessment through the development of fit-for-purpose in vitro assays.
McMullen PD, Andersen ME, Cholewa B, Clewell HJ 3rd, Dunnick KM, Hartman JK, Mansouri K, Minto MS, Nicolas CI, Phillips MB, Slattery S, Yoon M, Clewell RA. McMullen PD, et al. Among authors: nicolas ci. Toxicol In Vitro. 2018 Apr;48:310-317. doi: 10.1016/j.tiv.2018.01.027. Epub 2018 Jan 31. Toxicol In Vitro. 2018. PMID: 29391263 Free article. Review.
The role of fit-for-purpose assays within tiered testing approaches: A case study evaluating prioritized estrogen-active compounds in an in vitro human uterotrophic assay.
Beames T, Moreau M, Roberts LA, Mansouri K, Haider S, Smeltz M, Nicolas CI, Doheny D, Phillips MB, Yoon M, Becker RA, McMullen PD, Andersen ME, Clewell RA, Hartman JK. Beames T, et al. Among authors: nicolas ci. Toxicol Appl Pharmacol. 2020 Jan 15;387:114774. doi: 10.1016/j.taap.2019.114774. Epub 2019 Nov 27. Toxicol Appl Pharmacol. 2020. PMID: 31783037 Free article.
Application of a combined aggregate exposure pathway and adverse outcome pathway (AEP-AOP) approach to inform a cumulative risk assessment: A case study with phthalates.
Clewell RA, Leonard JA, Nicolas CI, Campbell JL, Yoon M, Efremenko AY, McMullen PD, Andersen ME, Clewell HJ 3rd, Phillips KA, Tan YM. Clewell RA, et al. Among authors: nicolas ci. Toxicol In Vitro. 2020 Aug;66:104855. doi: 10.1016/j.tiv.2020.104855. Epub 2020 Apr 8. Toxicol In Vitro. 2020. PMID: 32278033 Free PMC article.
Assessing Toxicokinetic Uncertainty and Variability in Risk Prioritization.
Wambaugh JF, Wetmore BA, Ring CL, Nicolas CI, Pearce RG, Honda GS, Dinallo R, Angus D, Gilbert J, Sierra T, Badrinarayanan A, Snodgrass B, Brockman A, Strock C, Setzer RW, Thomas RS. Wambaugh JF, et al. Among authors: nicolas ci. Toxicol Sci. 2019 Dec 1;172(2):235-251. doi: 10.1093/toxsci/kfz205. Toxicol Sci. 2019. PMID: 31532498 Free PMC article.
Tunable Doping in Graphene by Light-Switchable Molecules.
Shashikala HB, Nicolas CI, Wang XQ. Shashikala HB, et al. Among authors: nicolas ci. J Phys Chem C Nanomater Interfaces. 2012 Dec 13;116(49):26102-26105. doi: 10.1021/jp311269c. Epub 2012 Nov 22. J Phys Chem C Nanomater Interfaces. 2012. PMID: 23316261 Free PMC article.
11 results