Nicolaou KC - Search Results

1

Total Synthesis of Vancomycin Aglycon-Part 1: Synthesis of Amino Acids 4-7 and Construction of the AB-COD Ring Skeleton.

Nicolaou KC, Natarajan S, Li H, Jain NF, Hughes R, Solomon ME, Ramanjulu JM, Boddy CNC, Takayanagi M. Nicolaou KC, et al. Angew Chem Int Ed Engl. 1998 Oct 16;37(19):2708-2714. doi: 10.1002/(SICI)1521-3773(19981016)37:19<2708::AID-ANIE2708>3.0.CO;2-E. Angew Chem Int Ed Engl. 1998. PMID: 29711605

2

Total Synthesis of Vancomycin Aglycon-Part 2: Synthesis of Amino Acids 1-3 and Construction of the AB-COD-DOE Ring Skeleton.

Nicolaou KC, Jain NF, Natarajan S, Hughes R, Solomon ME, Li H, Ramanjulu JM, Takayanagi M, Koumbis AE, Bando T. Nicolaou KC, et al. Angew Chem Int Ed Engl. 1998 Oct 16;37(19):2714-2716. doi: 10.1002/(SICI)1521-3773(19981016)37:19<2714::AID-ANIE2714>3.0.CO;2-#. Angew Chem Int Ed Engl. 1998. PMID: 29711613

3

Total Synthesis of Vancomycin Aglycon-Part 3: Final Stages.

Nicolaou KC, Takayanagi M, Jain NF, Natarajan S, Koumbis AE, Bando T, Ramanjulu JM. Nicolaou KC, et al. Angew Chem Int Ed Engl. 1998 Oct 16;37(19):2717-2719. doi: 10.1002/(SICI)1521-3773(19981016)37:19<2717::AID-ANIE2717>3.0.CO;2-I. Angew Chem Int Ed Engl. 1998. PMID: 29711623

4

Does CIP Nomenclature Adequately Handle Molecules with Multiple Stereoelements? A Case Study of Vancomycin and Cognates We would like to thank Professor Dieter Hellwinkel for pointing out to us the stereochemical discrepancies in our review6 and elsewhere in the literature, and Kurt Mislow for stimulating and useful discussions.

Nicolaou KC, Boddy CN, Siegel JS. Nicolaou KC, et al. Angew Chem Int Ed Engl. 2001 Feb 16;40(4):701-704. Angew Chem Int Ed Engl. 2001. PMID: 11241596 No abstract available.

5

Atropselective macrocyclization of diaryl ether ring systems: application to the synthesis of vancomycin model systems.

Nicolaou KC, Boddy CN. Nicolaou KC, et al. J Am Chem Soc. 2002 Sep 4;124(35):10451-5. doi: 10.1021/ja020736r. J Am Chem Soc. 2002. PMID: 12197747

6

Target-Accelerated Combinatorial Synthesis and Discovery of Highly Potent Antibiotics Effective Against Vancomycin-Resistant Bacteria.

Nicolaou KC, Hughes R, Cho SY, Winssinger N, Smethurst C, Labischinski H, Endermann R. Nicolaou KC, et al. Angew Chem Int Ed Engl. 2000 Nov 3;39(21):3823-3828. doi: 10.1002/1521-3773(20001103)39:21<3823::AID-ANIE3823>3.0.CO;2-3. Angew Chem Int Ed Engl. 2000. PMID: 29711708 No abstract available.

7

Behind enemy lines.

Nicolaou KC, Boddy CN. Nicolaou KC, et al. Sci Am. 2001 May;284(5):54-61. doi: 10.1038/scientificamerican0501-54. Sci Am. 2001. PMID: 11341163 Review. No abstract available.

8

Solid- and solution-phase synthesis of vancomycin and vancomycin analogues with activity against vancomycin-resistant bacteria.

Nicolaou KC, Cho SY, Hughes R, Winssinger N, Smethurst C, Labischinski H, Endermann R. Nicolaou KC, et al. Chemistry. 2001 Sep 3;7(17):3798-823. doi: 10.1002/1521-3765(20010903)7:17<3798::aid-chem3798>3.0.co;2-6. Chemistry. 2001. PMID: 11575782

9

Synthesis and biological evaluation of vancomycin dimers with potent activity against vancomycin-resistant bacteria: target-accelerated combinatorial synthesis.

Nicolaou KC, Hughes R, Cho SY, Winssinger N, Labischinski H, Endermann R. Nicolaou KC, et al. Chemistry. 2001 Sep 3;7(17):3824-43. doi: 10.1002/1521-3765(20010903)7:17<3824::aid-chem3824>3.0.co;2-1. Chemistry. 2001. PMID: 11575783

10

Discovery and optimization of non-steroidal FXR agonists from natural product-like libraries.

Nicolaou KC, Evans RM, Roecker AJ, Hughes R, Downes M, Pfefferkorn JA. Nicolaou KC, et al. Org Biomol Chem. 2003 Mar 21;1(6):908-20. Org Biomol Chem. 2003. PMID: 12929628

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