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Microenvironment drug resistance in multiple myeloma: emerging new players.
Di Marzo L, Desantis V, Solimando AG, Ruggieri S, Annese T, Nico B, Fumarulo R, Vacca A, Frassanito MA. Di Marzo L, et al. Among authors: nico b. Oncotarget. 2016 Sep 13;7(37):60698-60711. doi: 10.18632/oncotarget.10849. Oncotarget. 2016. PMID: 27474171 Free PMC article. Review.
Novel targeting of phospho-cMET overcomes drug resistance and induces antitumor activity in multiple myeloma.
Moschetta M, Basile A, Ferrucci A, Frassanito MA, Rao L, Ria R, Solimando AG, Giuliani N, Boccarelli A, Fumarola F, Coluccia M, Rossini B, Ruggieri S, Nico B, Maiorano E, Ribatti D, Roccaro AM, Vacca A. Moschetta M, et al. Among authors: nico b. Clin Cancer Res. 2013 Aug 15;19(16):4371-82. doi: 10.1158/1078-0432.CCR-13-0039. Epub 2013 Jun 26. Clin Cancer Res. 2013. PMID: 23804425
HIF-1α of bone marrow endothelial cells implies relapse and drug resistance in patients with multiple myeloma and may act as a therapeutic target.
Ria R, Catacchio I, Berardi S, De Luisi A, Caivano A, Piccoli C, Ruggieri V, Frassanito MA, Ribatti D, Nico B, Annese T, Ruggieri S, Guarini A, Minoia C, Ditonno P, Angelucci E, Derudas D, Moschetta M, Dammacco F, Vacca A. Ria R, et al. Among authors: nico b. Clin Cancer Res. 2014 Feb 15;20(4):847-58. doi: 10.1158/1078-0432.CCR-13-1950. Epub 2013 Dec 2. Clin Cancer Res. 2014. PMID: 24297864
Inhibition of mTOR complex 2 restrains tumor angiogenesis in multiple myeloma.
Lamanuzzi A, Saltarella I, Desantis V, Frassanito MA, Leone P, Racanelli V, Nico B, Ribatti D, Ditonno P, Prete M, Solimando AG, Dammacco F, Vacca A, Ria R. Lamanuzzi A, et al. Among authors: nico b. Oncotarget. 2018 Apr 17;9(29):20563-20577. doi: 10.18632/oncotarget.25003. eCollection 2018 Apr 17. Oncotarget. 2018. PMID: 29755672 Free PMC article.
Bone marrow fibroblasts overexpress miR-27b and miR-214 in step with multiple myeloma progression, dependent on tumour cell-derived exosomes.
Frassanito MA, Desantis V, Di Marzo L, Craparotta I, Beltrame L, Marchini S, Annese T, Visino F, Arciuli M, Saltarella I, Lamanuzzi A, Solimando AG, Nico B, De Angelis M, Racanelli V, Mariggiò MA, Chiacchio R, Pizzuti M, Gallone A, Fumarulo R, D'Incalci M, Vacca A. Frassanito MA, et al. Among authors: nico b. J Pathol. 2019 Feb;247(2):241-253. doi: 10.1002/path.5187. J Pathol. 2019. PMID: 30357841
272 results