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Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology.
Golebiewska A, Hau AC, Oudin A, Stieber D, Yabo YA, Baus V, Barthelemy V, Klein E, Bougnaud S, Keunen O, Wantz M, Michelucci A, Neirinckx V, Muller A, Kaoma T, Nazarov PV, Azuaje F, De Falco A, Flies B, Richart L, Poovathingal S, Arns T, Grzyb K, Mock A, Herold-Mende C, Steino A, Brown D, May P, Miletic H, Malta TM, Noushmehr H, Kwon YJ, Jahn W, Klink B, Tanner G, Stead LF, Mittelbronn M, Skupin A, Hertel F, Bjerkvig R, Niclou SP. Golebiewska A, et al. Among authors: niclou sp. Acta Neuropathol. 2020 Dec;140(6):919-949. doi: 10.1007/s00401-020-02226-7. Epub 2020 Oct 3. Acta Neuropathol. 2020. PMID: 33009951 Free PMC article.
Cell therapies for glioblastoma.
Terzis AJ, Niclou SP, Rajcevic U, Danzeisen C, Bjerkvig R. Terzis AJ, et al. Among authors: niclou sp. Expert Opin Biol Ther. 2006 Aug;6(8):739-49. doi: 10.1517/14712598.6.8.739. Expert Opin Biol Ther. 2006. PMID: 16856796 Review.
iTRAQ-based proteomics profiling reveals increased metabolic activity and cellular cross-talk in angiogenic compared with invasive glioblastoma phenotype.
Rajcevic U, Petersen K, Knol JC, Loos M, Bougnaud S, Klychnikov O, Li KW, Pham TV, Wang J, Miletic H, Peng Z, Bjerkvig R, Jimenez CR, Niclou SP. Rajcevic U, et al. Among authors: niclou sp. Mol Cell Proteomics. 2009 Nov;8(11):2595-612. doi: 10.1074/mcp.M900124-MCP200. Epub 2009 Aug 12. Mol Cell Proteomics. 2009. PMID: 19674965 Free PMC article.
Cancer stem cells and angiogenesis.
Bjerkvig R, Johansson M, Miletic H, Niclou SP. Bjerkvig R, et al. Among authors: niclou sp. Semin Cancer Biol. 2009 Oct;19(5):279-84. doi: 10.1016/j.semcancer.2009.09.001. Epub 2009 Oct 7. Semin Cancer Biol. 2009. PMID: 19818406 Review.
Anti-VEGF treatment reduces blood supply and increases tumor cell invasion in glioblastoma.
Keunen O, Johansson M, Oudin A, Sanzey M, Rahim SA, Fack F, Thorsen F, Taxt T, Bartos M, Jirik R, Miletic H, Wang J, Stieber D, Stuhr L, Moen I, Rygh CB, Bjerkvig R, Niclou SP. Keunen O, et al. Among authors: niclou sp. Proc Natl Acad Sci U S A. 2011 Mar 1;108(9):3749-54. doi: 10.1073/pnas.1014480108. Epub 2011 Feb 14. Proc Natl Acad Sci U S A. 2011. PMID: 21321221 Free PMC article.
Novel ways to target brain tumour metabolism.
Stieber D, Abdul Rahim SA, Niclou SP. Stieber D, et al. Among authors: niclou sp. Expert Opin Ther Targets. 2011 Oct;15(10):1227-39. doi: 10.1517/14728222.2011.588211. Epub 2011 Jun 2. Expert Opin Ther Targets. 2011. PMID: 21635150 Review.
131 results