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B cell-intrinsic Myd88 regulates disease progression in murine lupus.
Tilstra JS, Kim M, Gordon RA, Leibler C, Cosgrove HA, Bastacky S, Nickerson KM, Shlomchik MJ. Tilstra JS, et al. Among authors: nickerson km. J Exp Med. 2023 Dec 4;220(12):e20230263. doi: 10.1084/jem.20230263. Epub 2023 Oct 3. J Exp Med. 2023. PMID: 37787782 Free PMC article.
B cell-intrinsic TLR9 expression is protective in murine lupus.
Tilstra JS, John S, Gordon RA, Leibler C, Kashgarian M, Bastacky S, Nickerson KM, Shlomchik MJ. Tilstra JS, et al. Among authors: nickerson km. J Clin Invest. 2020 Jun 1;130(6):3172-3187. doi: 10.1172/JCI132328. J Clin Invest. 2020. PMID: 32191633 Free PMC article.
Lupus and proliferative nephritis are PAD4 independent in murine models.
Gordon RA, Herter JM, Rosetti F, Campbell AM, Nishi H, Kashgarian M, Bastacky SI, Marinov A, Nickerson KM, Mayadas TN, Shlomchik MJ. Gordon RA, et al. Among authors: nickerson km. JCI Insight. 2017 May 18;2(10):e92926. doi: 10.1172/jci.insight.92926. eCollection 2017 May 18. JCI Insight. 2017. PMID: 28515361 Free PMC article.
Murine lupus is neutrophil elastase-independent in the MRL.Faslpr model.
Gordon RA, Tilstra JS, Marinov A, Nickerson KM, Bastacky SI, Shlomchik MJ. Gordon RA, et al. Among authors: nickerson km. PLoS One. 2020 Apr 3;15(4):e0226396. doi: 10.1371/journal.pone.0226396. eCollection 2020. PLoS One. 2020. PMID: 32243431 Free PMC article.
Genetic dissection of TLR9 reveals complex regulatory and cryptic proinflammatory roles in mouse lupus.
Leibler C, John S, Elsner RA, Thomas KB, Smita S, Joachim S, Levack RC, Callahan DJ, Gordon RA, Bastacky S, Fukui R, Miyake K, Gingras S, Nickerson KM, Shlomchik MJ. Leibler C, et al. Among authors: nickerson km. Nat Immunol. 2022 Oct;23(10):1457-1469. doi: 10.1038/s41590-022-01310-2. Epub 2022 Sep 23. Nat Immunol. 2022. PMID: 36151396 Free PMC article.
The Type II Anti-CD20 Antibody Obinutuzumab (GA101) Is More Effective Than Rituximab at Depleting B Cells and Treating Disease in a Murine Lupus Model.
Marinov AD, Wang H, Bastacky SI, van Puijenbroek E, Schindler T, Speziale D, Perro M, Klein C, Nickerson KM, Shlomchik MJ. Marinov AD, et al. Among authors: nickerson km. Arthritis Rheumatol. 2021 May;73(5):826-836. doi: 10.1002/art.41608. Epub 2021 Mar 24. Arthritis Rheumatol. 2021. PMID: 33277983 Free PMC article.
17 results