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Impaired neuron differentiation in GBA-associated Parkinson's disease is linked to cell cycle defects in organoids.
Rosety I, Zagare A, Saraiva C, Nickels S, Antony P, Almeida C, Glaab E, Halder R, Velychko S, Rauen T, Schöler HR, Bolognin S, Sauter T, Jarazo J, Krüger R, Schwamborn JC. Rosety I, et al. Among authors: nickels s. NPJ Parkinsons Dis. 2023 Dec 18;9(1):166. doi: 10.1038/s41531-023-00616-8. NPJ Parkinsons Dis. 2023. PMID: 38110400 Free PMC article.
FACS-Assisted CRISPR-Cas9 Genome Editing Facilitates Parkinson's Disease Modeling.
Arias-Fuenzalida J, Jarazo J, Qing X, Walter J, Gomez-Giro G, Nickels SL, Zaehres H, Schöler HR, Schwamborn JC. Arias-Fuenzalida J, et al. Stem Cell Reports. 2017 Nov 14;9(5):1423-1431. doi: 10.1016/j.stemcr.2017.08.026. Epub 2017 Oct 5. Stem Cell Reports. 2017. PMID: 28988985 Free PMC article.
3D Cultures of Parkinson's Disease-Specific Dopaminergic Neurons for High Content Phenotyping and Drug Testing.
Bolognin S, Fossépré M, Qing X, Jarazo J, Ščančar J, Moreno EL, Nickels SL, Wasner K, Ouzren N, Walter J, Grünewald A, Glaab E, Salamanca L, Fleming RMT, Antony PMA, Schwamborn JC. Bolognin S, et al. Among authors: nickels sl. Adv Sci (Weinh). 2018 Nov 20;6(1):1800927. doi: 10.1002/advs.201800927. eCollection 2019 Jan 9. Adv Sci (Weinh). 2018. PMID: 30643711 Free PMC article.
Neural Stem Cells of Parkinson's Disease Patients Exhibit Aberrant Mitochondrial Morphology and Functionality.
Walter J, Bolognin S, Antony PMA, Nickels SL, Poovathingal SK, Salamanca L, Magni S, Perfeito R, Hoel F, Qing X, Jarazo J, Arias-Fuenzalida J, Ignac T, Monzel AS, Gonzalez-Cano L, Pereira de Almeida L, Skupin A, Tronstad KJ, Schwamborn JC. Walter J, et al. Among authors: nickels sl. Stem Cell Reports. 2019 May 14;12(5):878-889. doi: 10.1016/j.stemcr.2019.03.004. Epub 2019 Apr 11. Stem Cell Reports. 2019. PMID: 30982740 Free PMC article.
Impaired serine metabolism complements LRRK2-G2019S pathogenicity in PD patients.
Nickels SL, Walter J, Bolognin S, Gérard D, Jaeger C, Qing X, Tisserand J, Jarazo J, Hemmer K, Harms A, Halder R, Lucarelli P, Berger E, Antony PMA, Glaab E, Hankemeier T, Klein C, Sauter T, Sinkkonen L, Schwamborn JC. Nickels SL, et al. Parkinsonism Relat Disord. 2019 Oct;67:48-55. doi: 10.1016/j.parkreldis.2019.09.018. Epub 2019 Sep 19. Parkinsonism Relat Disord. 2019. PMID: 31621607 Free article.
Machine learning-assisted neurotoxicity prediction in human midbrain organoids.
Monzel AS, Hemmer K, Kaoma T, Smits LM, Bolognin S, Lucarelli P, Rosety I, Zagare A, Antony P, Nickels SL, Krueger R, Azuaje F, Schwamborn JC. Monzel AS, et al. Among authors: nickels sl. Parkinsonism Relat Disord. 2020 Jun;75:105-109. doi: 10.1016/j.parkreldis.2020.05.011. Epub 2020 May 8. Parkinsonism Relat Disord. 2020. PMID: 32534431 Free article.
137 results