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Polyphosphate nanoparticles on the platelet surface trigger contact system activation.
Verhoef JJ, Barendrecht AD, Nickel KF, Dijkxhoorn K, Kenne E, Labberton L, McCarty OJ, Schiffelers R, Heijnen HF, Hendrickx AP, Schellekens H, Fens MH, de Maat S, Renné T, Maas C. Verhoef JJ, et al. Among authors: nickel kf. Blood. 2017 Mar 23;129(12):1707-1717. doi: 10.1182/blood-2016-08-734988. Epub 2017 Jan 3. Blood. 2017. PMID: 28049643 Free PMC article.
In vivo roles of factor XII.
Renné T, Schmaier AH, Nickel KF, Blombäck M, Maas C. Renné T, et al. Among authors: nickel kf. Blood. 2012 Nov 22;120(22):4296-303. doi: 10.1182/blood-2012-07-292094. Epub 2012 Sep 19. Blood. 2012. PMID: 22993391 Free PMC article. Review.
A factor XIIa inhibitory antibody provides thromboprotection in extracorporeal circulation without increasing bleeding risk.
Larsson M, Rayzman V, Nolte MW, Nickel KF, Björkqvist J, Jämsä A, Hardy MP, Fries M, Schmidbauer S, Hedenqvist P, Broomé M, Pragst I, Dickneite G, Wilson MJ, Nash AD, Panousis C, Renné T. Larsson M, et al. Among authors: nickel kf. Sci Transl Med. 2014 Feb 5;6(222):222ra17. doi: 10.1126/scitranslmed.3006804. Sci Transl Med. 2014. PMID: 24500405
In vivo activation and functions of the protease factor XII.
Björkqvist J, Nickel KF, Stavrou E, Renné T. Björkqvist J, et al. Among authors: nickel kf. Thromb Haemost. 2014 Nov;112(5):868-75. doi: 10.1160/TH14-04-0311. Epub 2014 Sep 4. Thromb Haemost. 2014. PMID: 25187064 Review.
Plasma contact system activation drives anaphylaxis in severe mast cell-mediated allergic reactions.
Sala-Cunill A, Björkqvist J, Senter R, Guilarte M, Cardona V, Labrador M, Nickel KF, Butler L, Luengo O, Kumar P, Labberton L, Long A, Di Gennaro A, Kenne E, Jämsä A, Krieger T, Schlüter H, Fuchs T, Flohr S, Hassiepen U, Cumin F, McCrae K, Maas C, Stavrou E, Renné T. Sala-Cunill A, et al. Among authors: nickel kf. J Allergy Clin Immunol. 2015 Apr;135(4):1031-1043.e6. doi: 10.1016/j.jaci.2014.07.057. Epub 2014 Sep 18. J Allergy Clin Immunol. 2015. PMID: 25240785
18 results