Nicke B - Search Results

1

Regulators of mitotic arrest and ceramide metabolism are determinants of sensitivity to paclitaxel and other chemotherapeutic drugs.

Swanton C, Marani M, Pardo O, Warne PH, Kelly G, Sahai E, Elustondo F, Chang J, Temple J, Ahmed AA, Brenton JD, Downward J, Nicke B. Swanton C, et al. Among authors: nicke b. Cancer Cell. 2007 Jun;11(6):498-512. doi: 10.1016/j.ccr.2007.04.011. Cancer Cell. 2007. PMID: 17560332 Free article.

2

Involvement of MINK, a Ste20 family kinase, in Ras oncogene-induced growth arrest in human ovarian surface epithelial cells.

Nicke B, Bastien J, Khanna SJ, Warne PH, Cowling V, Cook SJ, Peters G, Delpuech O, Schulze A, Berns K, Mullenders J, Beijersbergen RL, Bernards R, Ganesan TS, Downward J, Hancock DC. Nicke B, et al. Mol Cell. 2005 Dec 9;20(5):673-85. doi: 10.1016/j.molcel.2005.10.038. Mol Cell. 2005. PMID: 16337592 Free article.

3

Initiation of high frequency multi-drug resistance following kinase targeting by siRNAs.

Swanton C, Nicke B, Marani M, Kelly G, Downward J. Swanton C, et al. Among authors: nicke b. Cell Cycle. 2007 Aug 15;6(16):2001-4. doi: 10.4161/cc.6.16.4538. Epub 2007 Jun 4. Cell Cycle. 2007. PMID: 17721083

4

The extracellular matrix protein TGFBI induces microtubule stabilization and sensitizes ovarian cancers to paclitaxel.

Ahmed AA, Mills AD, Ibrahim AE, Temple J, Blenkiron C, Vias M, Massie CE, Iyer NG, McGeoch A, Crawford R, Nicke B, Downward J, Swanton C, Bell SD, Earl HM, Laskey RA, Caldas C, Brenton JD. Ahmed AA, et al. Among authors: nicke b. Cancer Cell. 2007 Dec;12(6):514-27. doi: 10.1016/j.ccr.2007.11.014. Cancer Cell. 2007. PMID: 18068629 Free PMC article.

5

The transcriptional response to Raf activation is almost completely dependent on Mitogen-activated Protein Kinase Kinase activity and shows a major autocrine component.

Schulze A, Nicke B, Warne PH, Tomlinson S, Downward J. Schulze A, et al. Among authors: nicke b. Mol Biol Cell. 2004 Jul;15(7):3450-63. doi: 10.1091/mbc.e03-11-0807. Epub 2004 Apr 16. Mol Biol Cell. 2004. PMID: 15090615 Free PMC article.

6

RNA interference, DNA methylation, and gene silencing: a bright future for cancer therapy?

Swanton C, Nicke B, Downward J. Swanton C, et al. Among authors: nicke b. Lancet Oncol. 2004 Nov;5(11):653-4. doi: 10.1016/S1470-2045(04)01604-3. Lancet Oncol. 2004. PMID: 15522650 No abstract available.

7

Binding of ras to phosphoinositide 3-kinase p110alpha is required for ras-driven tumorigenesis in mice.

Gupta S, Ramjaun AR, Haiko P, Wang Y, Warne PH, Nicke B, Nye E, Stamp G, Alitalo K, Downward J. Gupta S, et al. Among authors: nicke b. Cell. 2007 Jun 1;129(5):957-68. doi: 10.1016/j.cell.2007.03.051. Cell. 2007. PMID: 17540175 Free article.

8

Chromosomal instability determines taxane response.

Swanton C, Nicke B, Schuett M, Eklund AC, Ng C, Li Q, Hardcastle T, Lee A, Roy R, East P, Kschischo M, Endesfelder D, Wylie P, Kim SN, Chen JG, Howell M, Ried T, Habermann JK, Auer G, Brenton JD, Szallasi Z, Downward J. Swanton C, et al. Among authors: nicke b. Proc Natl Acad Sci U S A. 2009 May 26;106(21):8671-6. doi: 10.1073/pnas.0811835106. Epub 2009 May 19. Proc Natl Acad Sci U S A. 2009. PMID: 19458043 Free PMC article.

9

CERT depletion predicts chemotherapy benefit and mediates cytotoxic and polyploid-specific cancer cell death through autophagy induction.

Lee AJ, Roylance R, Sander J, Gorman P, Endesfelder D, Kschischo M, Jones NP, East P, Nicke B, Spassieva S, Obeid LM, Birkbak NJ, Szallasi Z, McKnight NC, Rowan AJ, Speirs V, Hanby AM, Downward J, Tooze SA, Swanton C. Lee AJ, et al. Among authors: nicke b. J Pathol. 2012 Feb;226(3):482-94. doi: 10.1002/path.2998. Epub 2011 Oct 19. J Pathol. 2012. PMID: 21953249

10

Concordance of exon array and real-time PCR assessment of gene expression following cancer cell cytotoxic drug exposure.

Lee AJ, East P, Pepper S, Nicke B, Szallasi Z, Eklund AC, Downward J, Swanton C. Lee AJ, et al. Among authors: nicke b. Cell Cycle. 2008 Dec 15;7(24):3947-8. doi: 10.4161/cc.7.24.7217. Epub 2008 Dec 17. Cell Cycle. 2008. PMID: 19066460 No abstract available.

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