Nick S. Laursen - Search Results

Year	Number of Results
2008	1
2010	1
2011	1
2012	2
2013	2
2015	1
2017	1
2018	4
2019	1
2020	8
2021	2
2022	3
2023	3
2024	0

1

Bispecific Complement Engagers for Targeted Complement Activation.

Pedersen DV, Gytz H, Winkler MBL, Zarantonello A, Baumann N, Hansen AG, Thiel S, Andersen GR, Valerius T, Laursen NS. Pedersen DV, et al. Among authors: laursen ns. J Immunol. 2023 Aug 1;211(3):403-413. doi: 10.4049/jimmunol.2200952. J Immunol. 2023. PMID: 37350633

2

Nanobody-mediated complement activation to kill HIV-infected cells.

Pedersen ML, Pedersen DV, Winkler MBL, Olesen HG, Søgaard OS, Østergaard L, Laursen NS, Rahimic AHF, Tolstrup M. Pedersen ML, et al. EMBO Mol Med. 2023 Apr 11;15(4):e16422. doi: 10.15252/emmm.202216422. Epub 2023 Feb 17. EMBO Mol Med. 2023. PMID: 36799046 Free PMC article.

3

Correction: A potent complement factor C3-specific nanobody inhibiting multiple functions in the alternative pathway of human and murine complement.

Jensen RK, Pihl R, Gadeberg TAF, Jensen JK, Andersen KR, Thiel S, Laursen NS, Andersen GR. Jensen RK, et al. Among authors: laursen ns. J Biol Chem. 2023 Feb;299(2):102951. doi: 10.1016/j.jbc.2023.102951. Epub 2023 Feb 4. J Biol Chem. 2023. PMID: 36739657 Free PMC article. No abstract available.

4

Structure-Guided Engineering of a Complement Component C3-Binding Nanobody Improves Specificity and Adds Cofactor Activity.

Pedersen H, Jensen RK, Hansen AG, Petersen SV, Thiel S, Laursen NS, Andersen GR. Pedersen H, et al. Front Immunol. 2022 Jul 22;13:872536. doi: 10.3389/fimmu.2022.872536. eCollection 2022. Front Immunol. 2022. PMID: 35935935 Free PMC article.

5

Structural insights into the function-modulating effects of nanobody binding to the integrin receptor α_Mβ₂.

Jensen RK, Pedersen H, Lorentzen J, Laursen NS, Vorup-Jensen T, Andersen GR. Jensen RK, et al. J Biol Chem. 2022 Aug;298(8):102168. doi: 10.1016/j.jbc.2022.102168. Epub 2022 Jun 20. J Biol Chem. 2022. PMID: 35738398 Free PMC article.

6

Nanobody-based human antibody formats act as IgE surrogate in hymenoptera venom allergy.

Aagaard JB, Sivelle C, Fischer M, Byskov K, Laursen NS, Pfützner W, Jakob T, Möbs C, Miehe M, Spillner E. Aagaard JB, et al. Among authors: laursen ns. Allergy. 2022 Sep;77(9):2859-2862. doi: 10.1111/all.15391. Epub 2022 Jun 9. Allergy. 2022. PMID: 35643911 Free PMC article. No abstract available.

7

Purification of Human Complement Component C4 and Sample Preparation for Structural Biology Applications.

Zarantonello A, Mortensen S, Laursen NS, Andersen GR. Zarantonello A, et al. Among authors: laursen ns. Methods Mol Biol. 2021;2227:249-264. doi: 10.1007/978-1-0716-1016-9_22. Methods Mol Biol. 2021. PMID: 33847947

8

Nanobodies Provide Insight into the Molecular Mechanisms of the Complement Cascade and Offer New Therapeutic Strategies.

Zarantonello A, Pedersen H, Laursen NS, Andersen GR. Zarantonello A, et al. Among authors: laursen ns. Biomolecules. 2021 Feb 17;11(2):298. doi: 10.3390/biom11020298. Biomolecules. 2021. PMID: 33671302 Free PMC article. Review.

9

A Complement C3-Specific Nanobody for Modulation of the Alternative Cascade Identifies the C-Terminal Domain of C3b as Functional in C5 Convertase Activity.

Pedersen H, Jensen RK, Jensen JMB, Fox R, Pedersen DV, Olesen HG, Hansen AG, Christiansen D, Mazarakis SMM, Lojek N, Hansen P, Gadeberg TAF, Zarantonello A, Laursen NS, Mollnes TE, Johnson MB, Stevens B, Thiel S, Andersen GR. Pedersen H, et al. Among authors: laursen ns. J Immunol. 2020 Oct 15;205(8):2287-2300. doi: 10.4049/jimmunol.2000752. Epub 2020 Sep 16. J Immunol. 2020. PMID: 32938727

10

Functional and Structural Characterization of a Potent C1q Inhibitor Targeting the Classical Pathway of the Complement System.

Laursen NS, Pedersen DV, Gytz H, Zarantonello A, Bernth Jensen JM, Hansen AG, Thiel S, Andersen GR. Laursen NS, et al. Front Immunol. 2020 Jul 17;11:1504. doi: 10.3389/fimmu.2020.01504. eCollection 2020. Front Immunol. 2020. PMID: 32849513 Free PMC article.

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