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Immune stress suppresses innate immune signaling in preleukemic precursor B-cells to provoke leukemia in predisposed mice.
Isidro-Hernández M, Casado-García A, Oak N, Alemán-Arteaga S, Ruiz-Corzo B, Martínez-Cano J, Mayado A, Sánchez EG, Blanco O, Gaspar ML, Orfao A, Alonso-López D, De Las Rivas J, Riesco S, Prieto-Matos P, González-Murillo Á, Criado FJG, Cenador MBG, Ramírez-Orellana M, de Andrés B, Vicente-Dueñas C, Cobaleda C, Nichols KE, Sánchez-García I. Isidro-Hernández M, et al. Among authors: nichols ke. Nat Commun. 2023 Aug 24;14(1):5159. doi: 10.1038/s41467-023-40961-z. Nat Commun. 2023. PMID: 37620322 Free PMC article.
Recent advances in Wilms' tumor predisposition.
Maciaszek JL, Oak N, Nichols KE. Maciaszek JL, et al. Among authors: nichols ke. Hum Mol Genet. 2020 Oct 20;29(R2):R138-R149. doi: 10.1093/hmg/ddaa091. Hum Mol Genet. 2020. PMID: 32412586 Review.
Molecular basis of ETV6-mediated predisposition to childhood acute lymphoblastic leukemia.
Nishii R, Baskin-Doerfler R, Yang W, Oak N, Zhao X, Yang W, Hoshitsuki K, Bloom M, Verbist K, Burns M, Li Z, Lin TN, Qian M, Moriyama T, Gastier-Foster JM, Rabin KR, Raetz E, Mullighan C, Pui CH, Yeoh AE, Zhang J, Metzger ML, Klco JM, Hunger SP, Newman S, Wu G, Loh ML, Nichols KE, Yang JJ. Nishii R, et al. Among authors: nichols ke. Blood. 2021 Jan 21;137(3):364-373. doi: 10.1182/blood.2020006164. Blood. 2021. PMID: 32693409 Free PMC article.
Transient Inhibition of the JAK/STAT Pathway Prevents B-ALL Development in Genetically Predisposed Mice.
Casado-García A, Isidro-Hernández M, Oak N, Mayado A, Mann-Ran C, Raboso-Gallego J, Alemán-Arteaga S, Buhles A, Sterker D, Sánchez EG, Martínez-Cano J, Blanco O, Orfao A, Alonso-López D, De Las Rivas J, Riesco S, Prieto-Matos P, González-Murillo Á, García Criado FJ, García Cenador MB, Radimerski T, Ramírez-Orellana M, Cobaleda C, Yang JJ, Vicente-Dueñas C, Weiss A, Nichols KE, Sánchez-García I. Casado-García A, et al. Among authors: nichols ke. Cancer Res. 2022 Mar 15;82(6):1098-1109. doi: 10.1158/0008-5472.CAN-21-3386. Cancer Res. 2022. PMID: 35131871 Free PMC article.
Towards the prevention of childhood leukemia.
Nichols KE, Sánchez-García I. Nichols KE, et al. Oncoscience. 2022 Apr 21;9:17-19. doi: 10.18632/oncoscience.553. eCollection 2022. Oncoscience. 2022. PMID: 35479646 Free PMC article. No abstract available.
Pathogenic Variants in Adult-Onset Cancer Predisposition Genes in Pediatric Cancer: Prevalence and Impact on Tumor Molecular Features and Clinical Management.
McGee RB, Oak N, Harrison L, Xu K, Nuccio R, Blake AK, Mostafavi R, Lewis S, Taylor LM, Kubal M, Ouma A, Hines-Dowell SJ, Cheng C, Furtado LV, Nichols KE. McGee RB, et al. Among authors: nichols ke. Clin Cancer Res. 2023 Apr 3;29(7):1243-1251. doi: 10.1158/1078-0432.CCR-22-2482. Clin Cancer Res. 2023. PMID: 36693186 Free PMC article.
269 results