Nicholls AW - Search Results

1

Genome-wide association study of metabolic traits reveals novel gene-metabolite-disease links.

Rueedi R, Ledda M, Nicholls AW, Salek RM, Marques-Vidal P, Morya E, Sameshima K, Montoliu I, Da Silva L, Collino S, Martin FP, Rezzi S, Steinbeck C, Waterworth DM, Waeber G, Vollenweider P, Beckmann JS, Le Coutre J, Mooser V, Bergmann S, Genick UK, Kutalik Z. Rueedi R, et al. Among authors: nicholls aw. PLoS Genet. 2014 Feb 20;10(2):e1004132. doi: 10.1371/journal.pgen.1004132. eCollection 2014 Feb. PLoS Genet. 2014. PMID: 24586186 Free PMC article.

2

Realising the potential of metabolomics.

Nicholls AW. Nicholls AW. Bioanalysis. 2012 Sep;4(18):2195-7. doi: 10.4155/bio.12.209. Bioanalysis. 2012. PMID: 23046260 Free article. No abstract available.

3

The analysis of acetaminophen (paracetamol) and seven metabolites in rat, pig and human plasma by U(H)PLC-MS.

Dargue R, Grant I, Nye LC, Nicholls A, Dare T, Stahl SH, Plumb RS, Lee K, Jalan R, Coen M, Wilson ID. Dargue R, et al. Bioanalysis. 2020 Apr;12(7):485-500. doi: 10.4155/bio-2020-0015. Epub 2020 Apr 28. Bioanalysis. 2020. PMID: 32343149 Free article.

4

The importance of experimental design and QC samples in large-scale and MS-driven untargeted metabolomic studies of humans.

Dunn WB, Wilson ID, Nicholls AW, Broadhurst D. Dunn WB, et al. Among authors: nicholls aw. Bioanalysis. 2012 Sep;4(18):2249-64. doi: 10.4155/bio.12.204. Bioanalysis. 2012. PMID: 23046267 Review.

5

Identification of phenacetin metabolites in human urine after administration of phenacetin-C2H3: measurement of futile metabolic deacetylation via HPLC/MS-SPE-NMR and HPLC-ToF MS.

Nicholls AW, Wilson ID, Godejohann M, Nicholson JK, Shockcor JP. Nicholls AW, et al. Xenobiotica. 2006 Jul;36(7):615-29. doi: 10.1080/00498250600711113. Xenobiotica. 2006. PMID: 16864507

6

Metabolism and Effects on Endogenous Metabolism of Paracetamol (Acetaminophen) in a Porcine Model of Liver Failure.

Dargue R, Zia R, Lau C, Nicholls AW, Dare TO, Lee K, Jalan R, Coen M, Wilson ID. Dargue R, et al. Among authors: nicholls aw. Toxicol Sci. 2020 May 1;175(1):87-97. doi: 10.1093/toxsci/kfaa023. Toxicol Sci. 2020. PMID: 32061126 Free PMC article.

7

Metabolomics dataset of PPAR-pan treated rat liver.

Ament Z, West JA, Stanley E, Li X, Ashmore T, Roberts LD, Wright J, Nicholls AW, Griffin JL. Ament Z, et al. Among authors: nicholls aw. Data Brief. 2016 May 10;8:196-202. doi: 10.1016/j.dib.2016.05.002. eCollection 2016 Sep. Data Brief. 2016. PMID: 27331087 Free PMC article.

8

Monic acid A: a biomarker in clinical intra-nasal mupirocin medication for MRSA decolonisation.

Dare TO, Nicholls AW, Mantle PG. Dare TO, et al. Among authors: nicholls aw. Biomarkers. 2019 Mar;24(2):131-133. doi: 10.1080/1354750X.2018.1514657. Epub 2018 Oct 25. Biomarkers. 2019. PMID: 30126316

9

Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry.

Dunn WB, Broadhurst D, Begley P, Zelena E, Francis-McIntyre S, Anderson N, Brown M, Knowles JD, Halsall A, Haselden JN, Nicholls AW, Wilson ID, Kell DB, Goodacre R; Human Serum Metabolome (HUSERMET) Consortium. Dunn WB, et al. Among authors: nicholls aw. Nat Protoc. 2011 Jun 30;6(7):1060-83. doi: 10.1038/nprot.2011.335. Nat Protoc. 2011. PMID: 21720319

10

Alterations in endo-lysosomal function induce similar hepatic lipid profiles in rodent models of drug-induced phospholipidosis and Sandhoff disease.

Lecommandeur E, Baker D, Cox TM, Nicholls AW, Griffin JL. Lecommandeur E, et al. Among authors: nicholls aw. J Lipid Res. 2017 Jul;58(7):1306-1314. doi: 10.1194/jlr.M073395. Epub 2017 Apr 4. J Lipid Res. 2017. PMID: 28377426 Free PMC article.

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