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Corticosteroid suppression of antiviral immunity increases bacterial loads and mucus production in COPD exacerbations.
Singanayagam A, Glanville N, Girkin JL, Ching YM, Marcellini A, Porter JD, Toussaint M, Walton RP, Finney LJ, Aniscenko J, Zhu J, Trujillo-Torralbo MB, Calderazzo MA, Grainge C, Loo SL, Veerati PC, Pathinayake PS, Nichol KS, Reid AT, James PL, Solari R, Wark PAB, Knight DA, Moffatt MF, Cookson WO, Edwards MR, Mallia P, Bartlett NW, Johnston SL. Singanayagam A, et al. Among authors: nichol ks. Nat Commun. 2018 Jun 8;9(1):2229. doi: 10.1038/s41467-018-04574-1. Nat Commun. 2018. PMID: 29884817 Free PMC article.
CSF3R/CD114 mediates infection-dependent transition to severe asthma.
Wang H, FitzPatrick M, Wilson NJ, Anthony D, Reading PC, Satzke C, Dunne EM, Licciardi PV, Seow HJ, Nichol K, Adcock IM, Chung KF, Anderson GP, Vlahos R, Wark P, Bozinovski S. Wang H, et al. J Allergy Clin Immunol. 2019 Feb;143(2):785-788.e6. doi: 10.1016/j.jaci.2018.10.001. Epub 2018 Oct 9. J Allergy Clin Immunol. 2019. PMID: 30312710 Free article. No abstract available.
Antiviral immunity is impaired in COPD patients with frequent exacerbations.
Singanayagam A, Loo SL, Calderazzo M, Finney LJ, Trujillo Torralbo MB, Bakhsoliani E, Girkin J, Veerati P, Pathinayake PS, Nichol KS, Reid A, Footitt J, Wark PAB, Grainge CL, Johnston SL, Bartlett NW, Mallia P. Singanayagam A, et al. Among authors: nichol ks. Am J Physiol Lung Cell Mol Physiol. 2019 Dec 1;317(6):L893-L903. doi: 10.1152/ajplung.00253.2019. Epub 2019 Sep 12. Am J Physiol Lung Cell Mol Physiol. 2019. PMID: 31513433 Free PMC article.
23 results