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In vitro Activity of Robenidine Analog NCL195 in Combination With Outer Membrane Permeabilizers Against Gram-Negative Bacterial Pathogens and Impact on Systemic Gram-Positive Bacterial Infection in Mice.
Pi H, Nguyen HT, Venter H, Boileau AR, Woolford L, Garg S, Page SW, Russell CC, Baker JR, McCluskey A, O'Donovan LA, Trott DJ, Ogunniyi AD. Pi H, et al. Among authors: nguyen ht. Front Microbiol. 2020 Aug 4;11:1556. doi: 10.3389/fmicb.2020.01556. eCollection 2020. Front Microbiol. 2020. PMID: 32849325 Free PMC article.
Oral administration of a 2-aminopyrimidine robenidine analogue (NCL195) significantly reduces Staphylococcus aureus infection and reduces Escherichia coli infection in combination with sub-inhibitory colistin concentrations in a bioluminescent mouse model.
Nguyen HT, Venter H, Woolford L, Young KA, McCluskey A, Garg S, Sapula SS, Page SW, Ogunniyi AD, Trott DJ. Nguyen HT, et al. Antimicrob Agents Chemother. 2023 Oct 18;67(10):e0042423. doi: 10.1128/aac.00424-23. Epub 2023 Sep 11. Antimicrob Agents Chemother. 2023. PMID: 37695304 Free PMC article.
Human iPSC and CRISPR targeted gene knock-in strategy for studying the somatic TIE2L914F mutation in endothelial cells.
Lazovic B, Nguyen HT, Ansarizadeh M, Wigge L, Kohl F, Li S, Carracedo M, Kettunen J, Krimpenfort L, Elgendy R, Richter K, De Silva L, Bilican B, Singh P, Saxena P, Hong X, Eklund L, Hicks R. Lazovic B, et al. Among authors: nguyen ht. Angiogenesis. 2024 May 21. doi: 10.1007/s10456-024-09925-9. Online ahead of print. Angiogenesis. 2024. PMID: 38771392
2,796 results