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Obesity is associated with hypothalamic injury in rodents and humans.
Thaler JP, Yi CX, Schur EA, Guyenet SJ, Hwang BH, Dietrich MO, Zhao X, Sarruf DA, Izgur V, Maravilla KR, Nguyen HT, Fischer JD, Matsen ME, Wisse BE, Morton GJ, Horvath TL, Baskin DG, Tschöp MH, Schwartz MW. Thaler JP, et al. Among authors: nguyen ht. J Clin Invest. 2012 Jan;122(1):153-62. doi: 10.1172/JCI59660. Epub 2011 Dec 27. J Clin Invest. 2012. PMID: 22201683 Free PMC article.
FGF19 action in the brain induces insulin-independent glucose lowering.
Morton GJ, Matsen ME, Bracy DP, Meek TH, Nguyen HT, Stefanovski D, Bergman RN, Wasserman DH, Schwartz MW. Morton GJ, et al. Among authors: nguyen ht. J Clin Invest. 2013 Nov;123(11):4799-808. doi: 10.1172/JCI70710. J Clin Invest. 2013. PMID: 24084738 Free PMC article.
Functional identification of a neurocircuit regulating blood glucose.
Meek TH, Nelson JT, Matsen ME, Dorfman MD, Guyenet SJ, Damian V, Allison MB, Scarlett JM, Nguyen HT, Thaler JP, Olson DP, Myers MG Jr, Schwartz MW, Morton GJ. Meek TH, et al. Among authors: nguyen ht. Proc Natl Acad Sci U S A. 2016 Apr 5;113(14):E2073-82. doi: 10.1073/pnas.1521160113. Epub 2016 Mar 21. Proc Natl Acad Sci U S A. 2016. PMID: 27001850 Free PMC article.
Deletion of Protein Kinase C λ in POMC Neurons Predisposes to Diet-Induced Obesity.
Dorfman MD, Krull JE, Scarlett JM, Guyenet SJ, Sajan MP, Damian V, Nguyen HT, Leitges M, Morton GJ, Farese RV, Schwartz MW, Thaler JP. Dorfman MD, et al. Among authors: nguyen ht. Diabetes. 2017 Apr;66(4):920-934. doi: 10.2337/db16-0482. Epub 2017 Jan 10. Diabetes. 2017. PMID: 28073831 Free PMC article.
2,787 results