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R-Loop Accumulation in Spliceosome Mutant Leukemias Confers Sensitivity to PARP1 Inhibition by Triggering Transcription-Replication Conflicts.
Liu ZS, Sinha S, Bannister M, Song A, Arriaga-Gomez E, McKeeken AJ, Bonner EA, Hanson BK, Sarchi M, Takashima K, Zong D, Corral VM, Nguyen E, Yoo J, Chiraphapphaiboon W, Leibson C, McMahon MC, Rai S, Swisher EM, Sachs Z, Chatla S, Stirewalt DL, Deeg HJ, Skorski T, Papapetrou EP, Walter MJ, Graubert TA, Doulatov S, Lee SC, Nguyen HD. Liu ZS, et al. Among authors: nguyen hd, nguyen e. Cancer Res. 2024 Feb 15;84(4):577-597. doi: 10.1158/0008-5472.CAN-23-3239. Cancer Res. 2024. PMID: 37967363
ATR inhibition disrupts rewired homologous recombination and fork protection pathways in PARP inhibitor-resistant BRCA-deficient cancer cells.
Yazinski SA, Comaills V, Buisson R, Genois MM, Nguyen HD, Ho CK, Todorova Kwan T, Morris R, Lauffer S, Nussenzweig A, Ramaswamy S, Benes CH, Haber DA, Maheswaran S, Birrer MJ, Zou L. Yazinski SA, et al. Among authors: nguyen hd. Genes Dev. 2017 Feb 1;31(3):318-332. doi: 10.1101/gad.290957.116. Epub 2017 Feb 27. Genes Dev. 2017. PMID: 28242626 Free PMC article.
Two distinct modes of ATR activation orchestrated by Rad17 and Nbs1.
Shiotani B, Nguyen HD, Håkansson P, Maréchal A, Tse A, Tahara H, Zou L. Shiotani B, et al. Among authors: nguyen hd. Cell Rep. 2013 May 30;3(5):1651-62. doi: 10.1016/j.celrep.2013.04.018. Epub 2013 May 16. Cell Rep. 2013. PMID: 23684611 Free PMC article.
Getting a Genomic View of DNA Replication Stress.
Zou L, Nguyen HD. Zou L, et al. Among authors: nguyen hd. Mol Cell. 2018 Oct 18;72(2):201-203. doi: 10.1016/j.molcel.2018.10.001. Mol Cell. 2018. PMID: 30340018 Free article.
622 results