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β2-spectrin (SPTBN1) as a therapeutic target for diet-induced liver disease and preventing cancer development.
Rao S, Yang X, Ohshiro K, Zaidi S, Wang Z, Shetty K, Xiang X, Hassan MI, Mohammad T, Latham PS, Nguyen BN, Wong L, Yu H, Al-Abed Y, Mishra B, Vacca M, Guenigault G, Allison MED, Vidal-Puig A, Benhammou JN, Alvarez M, Pajukanta P, Pisegna JR, Mishra L. Rao S, et al. Among authors: nguyen bn. Sci Transl Med. 2021 Dec 15;13(624):eabk2267. doi: 10.1126/scitranslmed.abk2267. Epub 2021 Dec 15. Sci Transl Med. 2021. PMID: 34910547 Free PMC article.
Loss of the transforming growth factor-β effector β2-Spectrin promotes genomic instability.
Chen J, Shukla V, Farci P, Andricovich J, Jogunoori W, Kwong LN, Katz LH, Shetty K, Rashid A, Su X, White J, Li L, Wang AY, Blechacz B, Raju GS, Davila M, Nguyen BN, Stroehlein JR, Chen J, Kim SS, Levin H, Machida K, Tsukamoto H, Michaely P, Tzatsos A, Mishra B, Amdur R, Mishra L. Chen J, et al. Among authors: nguyen bn. Hepatology. 2017 Feb;65(2):678-693. doi: 10.1002/hep.28927. Epub 2016 Dec 24. Hepatology. 2017. PMID: 28114741 Free PMC article.
Alcohol, stem cells and cancer.
Gu S, Nguyen BN, Rao S, Li S, Shetty K, Rashid A, Shukla V, Deng CX, Mishra L, Mishra B. Gu S, et al. Among authors: nguyen bn. Genes Cancer. 2017 Sep;8(9-10):695-700. doi: 10.18632/genesandcancer.156. Genes Cancer. 2017. PMID: 29234487 Free PMC article. Review.
Transforming growth factor-β in liver cancer stem cells and regeneration.
Rao S, Zaidi S, Banerjee J, Jogunoori W, Sebastian R, Mishra B, Nguyen BN, Wu RC, White J, Deng C, Amdur R, Li S, Mishra L. Rao S, et al. Among authors: nguyen bn. Hepatol Commun. 2017 Jul 21;1(6):477-493. doi: 10.1002/hep4.1062. eCollection 2017 Aug. Hepatol Commun. 2017. PMID: 29404474 Free PMC article. Review.
A Pan-Cancer Analysis Reveals High-Frequency Genetic Alterations in Mediators of Signaling by the TGF-β Superfamily.
Korkut A, Zaidi S, Kanchi RS, Rao S, Gough NR, Schultz A, Li X, Lorenzi PL, Berger AC, Robertson G, Kwong LN, Datto M, Roszik J, Ling S, Ravikumar V, Manyam G, Rao A, Shelley S, Liu Y, Ju Z, Hansel D, de Velasco G, Pennathur A, Andersen JB, O'Rourke CJ, Ohshiro K, Jogunoori W, Nguyen BN, Li S, Osmanbeyoglu HU, Ajani JA, Mani SA, Houseman A, Wiznerowicz M, Chen J, Gu S, Ma W, Zhang J, Tong P, Cherniack AD, Deng C, Resar L; Cancer Genome Atlas Research Network; Weinstein JN, Mishra L, Akbani R. Korkut A, et al. Among authors: nguyen bn. Cell Syst. 2018 Oct 24;7(4):422-437.e7. doi: 10.1016/j.cels.2018.08.010. Epub 2018 Sep 26. Cell Syst. 2018. PMID: 30268436 Free PMC article.
Mutated CEACAMs Disrupt Transforming Growth Factor Beta Signaling and Alter the Intestinal Microbiome to Promote Colorectal Carcinogenesis.
Gu S, Zaidi S, Hassan MI, Mohammad T, Malta TM, Noushmehr H, Nguyen B, Crandall KA, Srivastav J, Obias V, Lin P, Nguyen BN, Yao M, Yao R, King CH, Mazumder R, Mishra B, Rao S, Mishra L. Gu S, et al. Among authors: nguyen bn, nguyen b. Gastroenterology. 2020 Jan;158(1):238-252. doi: 10.1053/j.gastro.2019.09.023. Epub 2019 Oct 1. Gastroenterology. 2020. PMID: 31585122 Free PMC article.
Targeting the E3 Ubiquitin Ligase PJA1 Enhances Tumor-Suppressing TGFβ Signaling.
Chen J, Mitra A, Li S, Song S, Nguyen BN, Chen JS, Shin JH, Gough NR, Lin P, Obias V, He AR, Yao Z, Malta TM, Noushmehr H, Latham PS, Su X, Rashid A, Mishra B, Wu RC, Mishra L. Chen J, et al. Among authors: nguyen bn. Cancer Res. 2020 May 1;80(9):1819-1832. doi: 10.1158/0008-5472.CAN-19-3116. Epub 2020 Mar 3. Cancer Res. 2020. PMID: 32127355 Free PMC article.
Mice with dysfunctional TGF-β signaling develop altered intestinal microbiome and colorectal cancer resistant to 5FU.
Wang Z, Hopson LM, Singleton SS, Yang X, Jogunoori W, Mazumder R, Obias V, Lin P, Nguyen BN, Yao M, Miller L, White J, Rao S, Mishra L. Wang Z, et al. Among authors: nguyen bn. Biochim Biophys Acta Mol Basis Dis. 2021 Oct 1;1867(10):166179. doi: 10.1016/j.bbadis.2021.166179. Epub 2021 May 31. Biochim Biophys Acta Mol Basis Dis. 2021. PMID: 34082069 Free PMC article.
242 results