Ng PKS - Search Results

1

Cancer-associated mutations in the p85α N-terminal SH2 domain activate a spectrum of receptor tyrosine kinases.

Li X, Lau AYT, Ng ASN, Aldehaiman A, Zhou Y, Ng PKS, Arold ST, Cheung LWT. Li X, et al. Among authors: ng pks. Proc Natl Acad Sci U S A. 2021 Sep 14;118(37):e2101751118. doi: 10.1073/pnas.2101751118. Proc Natl Acad Sci U S A. 2021. PMID: 34507989 Free PMC article.

2

Naturally occurring neomorphic PIK3R1 mutations activate the MAPK pathway, dictating therapeutic response to MAPK pathway inhibitors.

Cheung LW, Yu S, Zhang D, Li J, Ng PK, Panupinthu N, Mitra S, Ju Z, Yu Q, Liang H, Hawke DH, Lu Y, Broaddus RR, Mills GB. Cheung LW, et al. Cancer Cell. 2014 Oct 13;26(4):479-94. doi: 10.1016/j.ccell.2014.08.017. Epub 2014 Oct 2. Cancer Cell. 2014. PMID: 25284480 Free PMC article.

3

Neomorphic PDGFRA extracellular domain driver mutations are resistant to PDGFRA targeted therapies.

Ip CKM, Ng PKS, Jeong KJ, Shao SH, Ju Z, Leonard PG, Hua X, Vellano CP, Woessner R, Sahni N, Scott KL, Mills GB. Ip CKM, et al. Among authors: ng pks. Nat Commun. 2018 Nov 2;9(1):4583. doi: 10.1038/s41467-018-06949-w. Nat Commun. 2018. PMID: 30389923 Free PMC article.

4

Therapeutic implications of activating noncanonical PIK3CA mutations in head and neck squamous cell carcinoma.

Jin N, Keam B, Cho J, Lee MJ, Kim HR, Torosyan H, Jura N, Ng PK, Mills GB, Li H, Zeng Y, Barbash Z, Tarcic G, Kang H, Bauman JE, Kim MO, VanLandingham NK, Swaney DL, Krogan NJ, Johnson DE, Grandis JR. Jin N, et al. J Clin Invest. 2021 Nov 15;131(22):e150335. doi: 10.1172/JCI150335. J Clin Invest. 2021. PMID: 34779417 Free PMC article.

5

Molecular Landscape of BRAF-Mutant NSCLC Reveals an Association Between Clonality and Driver Mutations and Identifies Targetable Non-V600 Driver Mutations.

Negrao MV, Raymond VM, Lanman RB, Robichaux JP, He J, Nilsson MB, Ng PKS, Amador BE, Roarty EB, Nagy RJ, Banks KC, Zhu VW, Ng C, Chae YK, Clarke JM, Crawford JA, Meric-Bernstam F, Ignatius Ou SH, Gandara DR, Heymach JV, Bivona TG, McCoach CE. Negrao MV, et al. Among authors: ng pks. J Thorac Oncol. 2020 Oct;15(10):1611-1623. doi: 10.1016/j.jtho.2020.05.021. Epub 2020 Jun 13. J Thorac Oncol. 2020. PMID: 32540409 Free PMC article.

6

RAC1 Alterations Induce Acquired Dabrafenib Resistance in Association with Anaplastic Transformation in a Papillary Thyroid Cancer Patient.

Bagheri-Yarmand R, Busaidy NL, McBeath E, Danysh BP, Evans KW, Moss TJ, Akcakanat A, Ng PKS, Knippler CM, Golden JA, Williams MD, Multani AS, Cabanillas ME, Shaw KR, Meric-Bernstam F, Shah MH, Ringel MD, Hofmann MC. Bagheri-Yarmand R, et al. Among authors: ng pks. Cancers (Basel). 2021 Sep 30;13(19):4950. doi: 10.3390/cancers13194950. Cancers (Basel). 2021. PMID: 34638434 Free PMC article.

7

Efficacy of futibatinib, an irreversible fibroblast growth factor receptor inhibitor, in FGFR-altered breast cancer.

Saridogan T, Akcakanat A, Zhao M, Evans KW, Yuca E, Scott S, Kirby BP, Zheng X, Ha MJ, Chen H, Ng PKS, DiPeri TP, Mills GB, Rodon Ahnert J, Damodaran S, Meric-Bernstam F. Saridogan T, et al. Among authors: ng pks. Sci Rep. 2023 Nov 18;13(1):20223. doi: 10.1038/s41598-023-46586-y. Sci Rep. 2023. PMID: 37980453 Free PMC article.

8

The Role of FAS Receptor Methylation in Osteosarcoma Metastasis.

Sun JM, Chow WY, Xu G, Hicks MJ, Nakka M, Shen J, Ng PKS, Taylor AM, Yu A, Farrar JE, Barkauskas DA, Gorlick R, Guidry Auvil JM, Gerhard D, Meltzer P, Guerra R, Man TK, Lau CC, On Behalf Of The Target Osteosarcoma Consortium. Sun JM, et al. Among authors: ng pks. Int J Mol Sci. 2023 Jul 29;24(15):12155. doi: 10.3390/ijms241512155. Int J Mol Sci. 2023. PMID: 37569529 Free PMC article.

9

Actionability classification of variants of unknown significance correlates with functional effect.

Johnson A, Ng PK, Kahle M, Castillo J, Amador B, Wang Y, Zeng J, Holla V, Vu T, Su F, Kim SH, Conway T, Jiang X, Chen K, Shaw KRM, Yap TA, Rodon J, Mills GB, Meric-Bernstam F. Johnson A, et al. NPJ Precis Oncol. 2023 Jul 15;7(1):67. doi: 10.1038/s41698-023-00420-w. NPJ Precis Oncol. 2023. PMID: 37454202 Free PMC article.

10

A functional genomic approach to actionable gene fusions for precision oncology.

Li J, Lu H, Ng PK, Pantazi A, Ip CKM, Jeong KJ, Amador B, Tran R, Tsang YH, Yang L, Song X, Dogruluk T, Ren X, Hadjipanayis A, Bristow CA, Lee S, Kucherlapati M, Parfenov M, Tang J, Seth S, Mahadeshwar HS, Mojumdar K, Zeng D, Zhang J, Protopopov A, Seidman JG, Creighton CJ, Lu Y, Sahni N, Shaw KR, Meric-Bernstam F, Futreal A, Chin L, Scott KL, Kucherlapati R, Mills GB, Liang H. Li J, et al. Sci Adv. 2022 Feb 11;8(6):eabm2382. doi: 10.1126/sciadv.abm2382. Epub 2022 Feb 9. Sci Adv. 2022. PMID: 35138907 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

49 results

Search Page