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Population-scale tissue transcriptomics maps long non-coding RNAs to complex disease.
de Goede OM, Nachun DC, Ferraro NM, Gloudemans MJ, Rao AS, Smail C, Eulalio TY, Aguet F, Ng B, Xu J, Barbeira AN, Castel SE, Kim-Hellmuth S, Park Y, Scott AJ, Strober BJ; GTEx Consortium; Brown CD, Wen X, Hall IM, Battle A, Lappalainen T, Im HK, Ardlie KG, Mostafavi S, Quertermous T, Kirkegaard K, Montgomery SB. de Goede OM, et al. Among authors: ng b. Cell. 2021 May 13;184(10):2633-2648.e19. doi: 10.1016/j.cell.2021.03.050. Epub 2021 Apr 16. Cell. 2021. PMID: 33864768 Free PMC article.
Integrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer's disease susceptibility.
Raj T, Li YI, Wong G, Humphrey J, Wang M, Ramdhani S, Wang YC, Ng B, Gupta I, Haroutunian V, Schadt EE, Young-Pearse T, Mostafavi S, Zhang B, Sklar P, Bennett DA, De Jager PL. Raj T, et al. Among authors: ng b. Nat Genet. 2018 Nov;50(11):1584-1592. doi: 10.1038/s41588-018-0238-1. Epub 2018 Oct 8. Nat Genet. 2018. PMID: 30297968 Free PMC article.
The TLR9 agonist (GNKG168) induces a unique immune activation pattern in vivo in children with minimal residual disease positive acute leukemia: Results of the TACL T2009-008 phase I study.
Ronsley R, Kariminia A, Ng B, Mostafavi S, Reid G, Subrt P, Hijiya N, Schultz KR. Ronsley R, et al. Among authors: ng b. Pediatr Hematol Oncol. 2019 Nov;36(8):468-481. doi: 10.1080/08880018.2019.1667461. Epub 2019 Sep 18. Pediatr Hematol Oncol. 2019. PMID: 31530240 Clinical Trial.
Deconvolving the contributions of cell-type heterogeneity on cortical gene expression.
Patrick E, Taga M, Ergun A, Ng B, Casazza W, Cimpean M, Yung C, Schneider JA, Bennett DA, Gaiteri C, De Jager PL, Bradshaw EM, Mostafavi S. Patrick E, et al. Among authors: ng b. PLoS Comput Biol. 2020 Aug 17;16(8):e1008120. doi: 10.1371/journal.pcbi.1008120. eCollection 2020 Aug. PLoS Comput Biol. 2020. PMID: 32804935 Free PMC article.
Deep learning of immune cell differentiation.
Maslova A, Ramirez RN, Ma K, Schmutz H, Wang C, Fox C, Ng B, Benoist C, Mostafavi S; Immunological Genome Project. Maslova A, et al. Among authors: ng b. Proc Natl Acad Sci U S A. 2020 Oct 13;117(41):25655-25666. doi: 10.1073/pnas.2011795117. Epub 2020 Sep 25. Proc Natl Acad Sci U S A. 2020. PMID: 32978299 Free PMC article.
1,348 results