Newton HJ - Search Results

1

Macrophage infectivity potentiator protein, a peptidyl prolyl cis-trans isomerase, essential for Coxiella burnetii growth and pathogenesis.

Debowski AW, Bzdyl NM, Thomas DR, Scott NE, Jenkins CH, Iwasaki J, Kibble EA, Khoo CA, Scheuplein NJ, Seibel PM, Lohr T, Metters G, Bond CS, Norville IH, Stubbs KA, Harmer NJ, Holzgrabe U, Newton HJ, Sarkar-Tyson M. Debowski AW, et al. Among authors: newton hj. PLoS Pathog. 2023 Jul 3;19(7):e1011491. doi: 10.1371/journal.ppat.1011491. eCollection 2023 Jul. PLoS Pathog. 2023. PMID: 37399210 Free PMC article.

2

Inhibition of inflammasome activation by Coxiella burnetii type IV secretion system effector IcaA.

Cunha LD, Ribeiro JM, Fernandes TD, Massis LM, Khoo CA, Moffatt JH, Newton HJ, Roy CR, Zamboni DS. Cunha LD, et al. Among authors: newton hj. Nat Commun. 2015 Dec 21;6:10205. doi: 10.1038/ncomms10205. Nat Commun. 2015. PMID: 26687278 Free PMC article.

3

The Effector Cig57 Hijacks FCHO-Mediated Vesicular Trafficking to Facilitate Intracellular Replication of Coxiella burnetii.

Latomanski EA, Newton P, Khoo CA, Newton HJ. Latomanski EA, et al. Among authors: newton hj, newton p. PLoS Pathog. 2016 Dec 21;12(12):e1006101. doi: 10.1371/journal.ppat.1006101. eCollection 2016 Dec. PLoS Pathog. 2016. PMID: 28002452 Free PMC article.

4

A Farnesylated Coxiella burnetii Effector Forms a Multimeric Complex at the Mitochondrial Outer Membrane during Infection.

Fielden LF, Moffatt JH, Kang Y, Baker MJ, Khoo CA, Roy CR, Stojanovski D, Newton HJ. Fielden LF, et al. Among authors: newton hj. Infect Immun. 2017 Apr 21;85(5):e01046-16. doi: 10.1128/IAI.01046-16. Print 2017 May. Infect Immun. 2017. PMID: 28242621 Free PMC article.

5

De novo NAD synthesis is required for intracellular replication of Coxiella burnetii, the causative agent of the neglected zoonotic disease Q fever.

Bitew MA, Khoo CA, Neha N, De Souza DP, Tull D, Wawegama NK, Newton HJ, Sansom FM. Bitew MA, et al. Among authors: newton hj. J Biol Chem. 2018 Nov 30;293(48):18636-18645. doi: 10.1074/jbc.RA118.005190. Epub 2018 Oct 12. J Biol Chem. 2018. PMID: 30315113 Free PMC article.

6

Genetic Manipulation of Non-pneumophila Legionella: Protocols Developed for Legionella longbeachae.

Korevaar E, Khoo CA, Newton HJ. Korevaar E, et al. Among authors: newton hj. Methods Mol Biol. 2019;1921:145-157. doi: 10.1007/978-1-4939-9048-1_9. Methods Mol Biol. 2019. PMID: 30694490

7

Loss of O-Linked Protein Glycosylation in Burkholderia cenocepacia Impairs Biofilm Formation and Siderophore Activity and Alters Transcriptional Regulators.

Oppy CC, Jebeli L, Kuba M, Oates CV, Strugnell R, Edgington-Mitchell LE, Valvano MA, Hartland EL, Newton HJ, Scott NE. Oppy CC, et al. Among authors: newton hj. mSphere. 2019 Nov 13;4(6):e00660-19. doi: 10.1128/mSphere.00660-19. mSphere. 2019. PMID: 31722994 Free PMC article.

8

Biogenesis of the Spacious Coxiella-Containing Vacuole Depends on Host Transcription Factors TFEB and TFE3.

Padmanabhan B, Fielden LF, Hachani A, Newton P, Thomas DR, Cho HJ, Khoo CA, Stojanovski D, Roy CR, Scott NE, Newton HJ. Padmanabhan B, et al. Among authors: newton hj, newton p. Infect Immun. 2020 Feb 20;88(3):e00534-19. doi: 10.1128/IAI.00534-19. Print 2020 Feb 20. Infect Immun. 2020. PMID: 31818957 Free PMC article.

9

Meso-tartrate inhibits intracellular replication of Coxiella burnetii, the causative agent of the zoonotic disease Q fever.

Bitew MA, Wawegama NK, Newton HJ, Sansom FM. Bitew MA, et al. Among authors: newton hj. Pathog Dis. 2019 Nov 1;77(8):ftz066. doi: 10.1093/femspd/ftz066. Pathog Dis. 2019. PMID: 31845968

10

Lysosomal degradation products induce Coxiella burnetii virulence.

Newton P, Thomas DR, Reed SCO, Lau N, Xu B, Ong SY, Pasricha S, Madhamshettiwar PB, Edgington-Mitchell LE, Simpson KJ, Roy CR, Newton HJ. Newton P, et al. Among authors: newton hj. Proc Natl Acad Sci U S A. 2020 Mar 24;117(12):6801-6810. doi: 10.1073/pnas.1921344117. Epub 2020 Mar 9. Proc Natl Acad Sci U S A. 2020. PMID: 32152125 Free PMC article.

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