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Liraglutide safety and efficacy in patients with non-alcoholic steatohepatitis (LEAN): a multicentre, double-blind, randomised, placebo-controlled phase 2 study.
Armstrong MJ, Gaunt P, Aithal GP, Barton D, Hull D, Parker R, Hazlehurst JM, Guo K; LEAN trial team; Abouda G, Aldersley MA, Stocken D, Gough SC, Tomlinson JW, Brown RM, Hübscher SG, Newsome PN. Armstrong MJ, et al. Among authors: newsome pn. Lancet. 2016 Feb 13;387(10019):679-690. doi: 10.1016/S0140-6736(15)00803-X. Epub 2015 Nov 20. Lancet. 2016. PMID: 26608256 Free article. Clinical Trial.
Guidelines for liver transplantation for patients with non-alcoholic steatohepatitis.
Newsome PN, Allison ME, Andrews PA, Auzinger G, Day CP, Ferguson JW, Henriksen PA, Hubscher SG, Manley H, McKiernan PJ, Millson C, Mirza D, Neuberger JM, Oben J, Pollard S, Simpson KJ, Thorburn D, Tomlinson JW, Wyatt JS; British Transplant Society. Newsome PN, et al. Gut. 2012 Apr;61(4):484-500. doi: 10.1136/gutjnl-2011-300886. Epub 2012 Jan 10. Gut. 2012. PMID: 22234978 No abstract available.
Loss of 5α-reductase type 1 accelerates the development of hepatic steatosis but protects against hepatocellular carcinoma in male mice.
Dowman JK, Hopkins LJ, Reynolds GM, Armstrong MJ, Nasiri M, Nikolaou N, van Houten EL, Visser JA, Morgan SA, Lavery GG, Oprescu A, Hübscher SG, Newsome PN, Tomlinson JW. Dowman JK, et al. Among authors: newsome pn. Endocrinology. 2013 Dec;154(12):4536-47. doi: 10.1210/en.2013-1592. Epub 2013 Sep 30. Endocrinology. 2013. PMID: 24080367 Free PMC article.
Severe asymptomatic non-alcoholic fatty liver disease in routine diabetes care; a multi-disciplinary team approach to diagnosis and management.
Armstrong MJ, Hazlehurst JM, Parker R, Koushiappi E, Mann J, Khan S, Philips A, Chandler L, Johnson J, Round M, Haydon G, Karamat MA, Newsome PN, Tomlinson JW. Armstrong MJ, et al. Among authors: newsome pn. QJM. 2014 Jan;107(1):33-41. doi: 10.1093/qjmed/hct198. Epub 2013 Oct 15. QJM. 2014. PMID: 24131545 Free PMC article.
Liraglutide efficacy and action in non-alcoholic steatohepatitis (LEAN): study protocol for a phase II multicentre, double-blinded, randomised, controlled trial.
Armstrong MJ, Barton D, Gaunt P, Hull D, Guo K, Stocken D, Gough SC, Tomlinson JW, Brown RM, Hübscher SG, Newsome PN; LEAN trial team. Armstrong MJ, et al. Among authors: newsome pn. BMJ Open. 2013 Nov 4;3(11):e003995. doi: 10.1136/bmjopen-2013-003995. BMJ Open. 2013. PMID: 24189085 Free PMC article.
Development of hepatocellular carcinoma in a murine model of nonalcoholic steatohepatitis induced by use of a high-fat/fructose diet and sedentary lifestyle.
Dowman JK, Hopkins LJ, Reynolds GM, Nikolaou N, Armstrong MJ, Shaw JC, Houlihan DD, Lalor PF, Tomlinson JW, Hübscher SG, Newsome PN. Dowman JK, et al. Among authors: newsome pn. Am J Pathol. 2014 May;184(5):1550-61. doi: 10.1016/j.ajpath.2014.01.034. Epub 2014 Mar 17. Am J Pathol. 2014. PMID: 24650559 Free PMC article.
220 results