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Lead optimization toward proof-of-concept tools for Huntington's disease within a 4-(1H-pyrazol-4-yl)pyrimidine class of pan-JNK inhibitors.
Wityak J, McGee KF, Conlon MP, Song RH, Duffy BC, Clayton B, Lynch M, Wang G, Freeman E, Haber J, Kitchen DB, Manning DD, Ismail J, Khmelnitsky Y, Michels P, Webster J, Irigoyen M, Luche M, Hultman M, Bai M, Kuok ID, Newell R, Lamers M, Leonard P, Yates D, Matthews K, Ongeri L, Clifton S, Mead T, Deupree S, Wheelan P, Lyons K, Wilson C, Kiselyov A, Toledo-Sherman L, Beconi M, Muñoz-Sanjuan I, Bard J, Dominguez C. Wityak J, et al. Among authors: newell r. J Med Chem. 2015 Apr 9;58(7):2967-87. doi: 10.1021/jm5013598. Epub 2015 Mar 19. J Med Chem. 2015. PMID: 25760409
Impact of fed-batch process intensification on the productivity and product quality of two CHO cell lines expressing unique novel molecular format proteins.
Wolnick NQ, Dickson MR, Webster TA, Connolly RP, Fernandes N, Encheva V, Crittenden H, Hodgkins J, Hadley BC, Palermo G, Hendrick SJ, Newell RA, Gray G, Siltanen C, Armstrong J, Downey BJ, Mason C. Wolnick NQ, et al. Among authors: newell ra. Bioprocess Biosyst Eng. 2024 Apr 23. doi: 10.1007/s00449-024-02997-3. Online ahead of print. Bioprocess Biosyst Eng. 2024. PMID: 38653840
Switching Lead for Tin in PbHfO3 : Noncubic Structure of SnHfO3.
Gabilondo EA, Newell RJ, Broughton R, Koldemir A, Pöttgen R, Jones JL, Maggard PA. Gabilondo EA, et al. Among authors: newell rj. Angew Chem Int Ed Engl. 2024 Jan 22;63(4):e202312130. doi: 10.1002/anie.202312130. Epub 2023 Sep 25. Angew Chem Int Ed Engl. 2024. PMID: 37699142
US benefit-cost analysis requires revision.
Howard PH, Sarinsky M, Bauer M, Cecot C, Cropper M, Drupp M, Freeman M, Gillingham KT, Gollier C, Groom B, Li Q, Livermore M, Newell R, Pizer WA, Prest B, Rudebusch G, Sterner T, Wagner G. Howard PH, et al. Among authors: newell r. Science. 2023 May 26;380(6647):803. doi: 10.1126/science.adi5943. Epub 2023 May 25. Science. 2023. PMID: 37228186 No abstract available.
256 results