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TLR4 genotype and environmental LPS mediate RSV bronchiolitis through Th2 polarization.
Caballero MT, Serra ME, Acosta PL, Marzec J, Gibbons L, Salim M, Rodriguez A, Reynaldi A, Garcia A, Bado D, Buchholz UJ, Hijano DR, Coviello S, Newcomb D, Bellabarba M, Ferolla FM, Libster R, Berenstein A, Siniawaski S, Blumetti V, Echavarria M, Pinto L, Lawrence A, Ossorio MF, Grosman A, Mateu CG, Bayle C, Dericco A, Pellegrini M, Igarza I, Repetto HA, Grimaldi LA, Gudapati P, Polack NR, Althabe F, Shi M, Ferrero F, Bergel E, Stein RT, Peebles RS, Boothby M, Kleeberger SR, Polack FP. Caballero MT, et al. Among authors: newcomb d. J Clin Invest. 2015 Feb;125(2):571-82. doi: 10.1172/JCI75183. Epub 2015 Jan 2. J Clin Invest. 2015. PMID: 25555213 Free PMC article. Clinical Trial.
A chimeric A2 strain of respiratory syncytial virus (RSV) with the fusion protein of RSV strain line 19 exhibits enhanced viral load, mucus, and airway dysfunction.
Moore ML, Chi MH, Luongo C, Lukacs NW, Polosukhin VV, Huckabee MM, Newcomb DC, Buchholz UJ, Crowe JE Jr, Goleniewska K, Williams JV, Collins PL, Peebles RS Jr. Moore ML, et al. J Virol. 2009 May;83(9):4185-94. doi: 10.1128/JVI.01853-08. Epub 2009 Feb 11. J Virol. 2009. PMID: 19211758 Free PMC article.
Bugs and asthma: a different disease?
Newcomb DC, Peebles RS Jr. Newcomb DC, et al. Proc Am Thorac Soc. 2009 May 1;6(3):266-71. doi: 10.1513/pats.200806-056RM. Proc Am Thorac Soc. 2009. PMID: 19387028 Free PMC article. Review.
PGI2 as a regulator of CD4+ subset differentiation and function.
Boswell MG, Zhou W, Newcomb DC, Peebles RS Jr. Boswell MG, et al. Prostaglandins Other Lipid Mediat. 2011 Nov;96(1-4):21-6. doi: 10.1016/j.prostaglandins.2011.08.003. Epub 2011 Aug 12. Prostaglandins Other Lipid Mediat. 2011. PMID: 21864703 Free PMC article. Review.
IL-13 regulates Th17 secretion of IL-17A in an IL-10-dependent manner.
Newcomb DC, Boswell MG, Huckabee MM, Goleniewska K, Dulek DE, Reiss S, Lukacs NW, Kolls JK, Peebles RS Jr. Newcomb DC, et al. J Immunol. 2012 Feb 1;188(3):1027-35. doi: 10.4049/jimmunol.1102216. Epub 2011 Dec 30. J Immunol. 2012. PMID: 22210911 Free PMC article.
131 results