Newby GA - Search Results

1

Evolution of an adenine base editor into a small, efficient cytosine base editor with low off-target activity.

Neugebauer ME, Hsu A, Arbab M, Krasnow NA, McElroy AN, Pandey S, Doman JL, Huang TP, Raguram A, Banskota S, Newby GA, Tolar J, Osborn MJ, Liu DR. Neugebauer ME, et al. Among authors: newby ga. Nat Biotechnol. 2023 May;41(5):673-685. doi: 10.1038/s41587-022-01533-6. Epub 2022 Nov 10. Nat Biotechnol. 2023. PMID: 36357719 Free PMC article.

2

Persistent Activation of mRNA Translation by Transient Hsp90 Inhibition.

Tsvetkov P, Eisen TJ, Heinrich SU, Brune Z, Hallacli E, Newby GA, Kayatekin C, Pincus D, Lindquist S. Tsvetkov P, et al. Among authors: newby ga. Cell Rep. 2020 Sep 8;32(10):108149. doi: 10.1016/j.celrep.2020.108149. Cell Rep. 2020. PMID: 32905780 Free article. No abstract available.

3

Persistent Activation of mRNA Translation by Transient Hsp90 Inhibition.

Tsvetkov P, Eisen TJ, Heinrich SU, Brune Z, Hallacli E, Newby GA, Kayatekin C, Pincus D, Lindquist S. Tsvetkov P, et al. Among authors: newby ga. Cell Rep. 2020 Aug 11;32(6):108001. doi: 10.1016/j.celrep.2020.108001. Cell Rep. 2020. PMID: 32783929 Free PMC article.

4

Generation of Fluorogen-Activating Designed Ankyrin Repeat Proteins (FADAs) as Versatile Sensor Tools.

Schütz M, Batyuk A, Klenk C, Kummer L, de Picciotto S, Gülbakan B, Wu Y, Newby GA, Zosel F, Schöppe J, Sedlák E, Mittl PRE, Zenobi R, Wittrup KD, Plückthun A. Schütz M, et al. Among authors: newby ga. J Mol Biol. 2016 Mar 27;428(6):1272-1289. doi: 10.1016/j.jmb.2016.01.017. Epub 2016 Jan 23. J Mol Biol. 2016. PMID: 26812208

5

Improving cytidine and adenine base editors by expression optimization and ancestral reconstruction.

Koblan LW, Doman JL, Wilson C, Levy JM, Tay T, Newby GA, Maianti JP, Raguram A, Liu DR. Koblan LW, et al. Among authors: newby ga. Nat Biotechnol. 2018 Oct;36(9):843-846. doi: 10.1038/nbt.4172. Epub 2018 May 29. Nat Biotechnol. 2018. PMID: 29813047 Free PMC article.

6

Continuous evolution of base editors with expanded target compatibility and improved activity.

Thuronyi BW, Koblan LW, Levy JM, Yeh WH, Zheng C, Newby GA, Wilson C, Bhaumik M, Shubina-Oleinik O, Holt JR, Liu DR. Thuronyi BW, et al. Among authors: newby ga. Nat Biotechnol. 2019 Sep;37(9):1070-1079. doi: 10.1038/s41587-019-0193-0. Epub 2019 Jul 22. Nat Biotechnol. 2019. PMID: 31332326 Free PMC article.

7

Publisher Correction: Continuous evolution of base editors with expanded target compatibility and improved activity.

Thuronyi BW, Koblan LW, Levy JM, Yeh WH, Zheng C, Newby GA, Wilson C, Bhaumik M, Shubina-Oleinik O, Holt JR, Liu DR. Thuronyi BW, et al. Among authors: newby ga. Nat Biotechnol. 2019 Sep;37(9):1091. doi: 10.1038/s41587-019-0253-5. Nat Biotechnol. 2019. PMID: 31406330

8

Base Editor Correction of COL7A1 in Recessive Dystrophic Epidermolysis Bullosa Patient-Derived Fibroblasts and iPSCs.

Osborn MJ, Newby GA, McElroy AN, Knipping F, Nielsen SC, Riddle MJ, Xia L, Chen W, Eide CR, Webber BR, Wandall HH, Dabelsteen S, Blazar BR, Liu DR, Tolar J. Osborn MJ, et al. Among authors: newby ga. J Invest Dermatol. 2020 Feb;140(2):338-347.e5. doi: 10.1016/j.jid.2019.07.701. Epub 2019 Aug 19. J Invest Dermatol. 2020. PMID: 31437443 Free PMC article.

9

Search-and-replace genome editing without double-strand breaks or donor DNA.

Anzalone AV, Randolph PB, Davis JR, Sousa AA, Koblan LW, Levy JM, Chen PJ, Wilson C, Newby GA, Raguram A, Liu DR. Anzalone AV, et al. Among authors: newby ga. Nature. 2019 Dec;576(7785):149-157. doi: 10.1038/s41586-019-1711-4. Epub 2019 Oct 21. Nature. 2019. PMID: 31634902 Free PMC article.

10

Evaluation and minimization of Cas9-independent off-target DNA editing by cytosine base editors.

Doman JL, Raguram A, Newby GA, Liu DR. Doman JL, et al. Among authors: newby ga. Nat Biotechnol. 2020 May;38(5):620-628. doi: 10.1038/s41587-020-0414-6. Epub 2020 Feb 10. Nat Biotechnol. 2020. PMID: 32042165 Free PMC article.

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