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Genome homeostasis defects drive enlarged cells into senescence.
Manohar S, Estrada ME, Uliana F, Vuina K, Alvarez PM, de Bruin RAM, Neurohr GE. Manohar S, et al. Among authors: neurohr ge. Mol Cell. 2023 Nov 16;83(22):4032-4046.e6. doi: 10.1016/j.molcel.2023.10.018. Epub 2023 Nov 16. Mol Cell. 2023. PMID: 37977116 Free PMC article.
Relevance and Regulation of Cell Density.
Neurohr GE, Amon A. Neurohr GE, et al. Trends Cell Biol. 2020 Mar;30(3):213-225. doi: 10.1016/j.tcb.2019.12.006. Epub 2020 Jan 21. Trends Cell Biol. 2020. PMID: 31980346 Free PMC article. Review.
Excessive Cell Growth Causes Cytoplasm Dilution And Contributes to Senescence.
Neurohr GE, Terry RL, Lengefeld J, Bonney M, Brittingham GP, Moretto F, Miettinen TP, Vaites LP, Soares LM, Paulo JA, Harper JW, Buratowski S, Manalis S, van Werven FJ, Holt LJ, Amon A. Neurohr GE, et al. Cell. 2019 Feb 21;176(5):1083-1097.e18. doi: 10.1016/j.cell.2019.01.018. Epub 2019 Feb 7. Cell. 2019. PMID: 30739799 Free PMC article.