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A Trem2R47H mouse model without cryptic splicing drives age- and disease-dependent tissue damage and synaptic loss in response to plaques.
Tran KM, Kawauchi S, Kramár EA, Rezaie N, Liang HY, Sakr JS, Gomez-Arboledas A, Arreola MA, Cunha CD, Phan J, Wang S, Collins S, Walker A, Shi KX, Neumann J, Filimban G, Shi Z, Milinkeviciute G, Javonillo DI, Tran K, Gantuz M, Forner S, Swarup V, Tenner AJ, LaFerla FM, Wood MA, Mortazavi A, MacGregor GR, Green KN. Tran KM, et al. Among authors: neumann j. Mol Neurodegener. 2023 Feb 17;18(1):12. doi: 10.1186/s13024-023-00598-4. Mol Neurodegener. 2023. PMID: 36803190 Free PMC article.
Delineating the role of MITF isoforms in pigmentation and tissue homeostasis.
Flesher JL, Paterson-Coleman EK, Vasudeva P, Ruiz-Vega R, Marshall M, Pearlman E, MacGregor GR, Neumann J, Ganesan AK. Flesher JL, et al. Among authors: neumann j. Pigment Cell Melanoma Res. 2020 Mar;33(2):279-292. doi: 10.1111/pcmr.12828. Epub 2019 Oct 16. Pigment Cell Melanoma Res. 2020. PMID: 31562697 Free PMC article.
Interneuron Dysfunction in a New Mouse Model of SCN1A GEFS.
Das A, Zhu B, Xie Y, Zeng L, Pham AT, Neumann JC, Safrina O, Benavides DR, MacGregor GR, Schutte SS, Hunt RF, O'Dowd DK. Das A, et al. eNeuro. 2021 Apr 12;8(2):ENEURO.0394-20.2021. doi: 10.1523/ENEURO.0394-20.2021. Print 2021 Mar-Apr. eNeuro. 2021. PMID: 33658306 Free PMC article.
Systematic phenotyping and characterization of the 5xFAD mouse model of Alzheimer's disease.
Forner S, Kawauchi S, Balderrama-Gutierrez G, Kramár EA, Matheos DP, Phan J, Javonillo DI, Tran KM, Hingco E, da Cunha C, Rezaie N, Alcantara JA, Baglietto-Vargas D, Jansen C, Neumann J, Wood MA, MacGregor GR, Mortazavi A, Tenner AJ, LaFerla FM, Green KN. Forner S, et al. Among authors: neumann j. Sci Data. 2021 Oct 15;8(1):270. doi: 10.1038/s41597-021-01054-y. Sci Data. 2021. PMID: 34654824 Free PMC article.
Systematic Phenotyping and Characterization of the 3xTg-AD Mouse Model of Alzheimer's Disease.
Javonillo DI, Tran KM, Phan J, Hingco E, Kramár EA, da Cunha C, Forner S, Kawauchi S, Milinkeviciute G, Gomez-Arboledas A, Neumann J, Banh CE, Huynh M, Matheos DP, Rezaie N, Alcantara JA, Mortazavi A, Wood MA, Tenner AJ, MacGregor GR, Green KN, LaFerla FM. Javonillo DI, et al. Among authors: neumann j. Front Neurosci. 2022 Jan 24;15:785276. doi: 10.3389/fnins.2021.785276. eCollection 2021. Front Neurosci. 2022. PMID: 35140584 Free PMC article.
Tlr5 deficiency exacerbates lupus-like disease in the MRL/lpr mouse model.
Alajoleen RM, Oakland DN, Estaleen R, Shakeri A, Lu R, Appiah M, Sun S, Neumann J, Kawauchi S, Cecere TE, McMillan RP, Reilly CM, Luo XM. Alajoleen RM, et al. Among authors: neumann j. Front Immunol. 2024 Jan 30;15:1359534. doi: 10.3389/fimmu.2024.1359534. eCollection 2024. Front Immunol. 2024. PMID: 38352866 Free PMC article.
BIN1K358R suppresses glial response to plaques in mouse model of Alzheimer's disease.
Garcia-Agudo LF, Shi Z, Smith IF, Kramár EA, Tran K, Kawauchi S, Wang S, Collins S, Walker A, Shi KX, Neumann J, Liang HY, Da Cunha C, Milinkeviciute G, Morabito S, Miyoshi E, Rezaie N, Gomez-Arboledas A, Arvilla AM, Ghaemi DI, Tenner AJ, LaFerla FM, Wood MA, Mortazavi A, Swarup V, MacGregor GR, Green KN. Garcia-Agudo LF, et al. Among authors: neumann j. Alzheimers Dement. 2024 Apr;20(4):2922-2942. doi: 10.1002/alz.13767. Epub 2024 Mar 9. Alzheimers Dement. 2024. PMID: 38460121 Free PMC article.
The Abca7V1613M variant reduces Aβ generation, plaque load, and neuronal damage.
Butler CA, Mendoza Arvilla A, Milinkeviciute G, Da Cunha C, Kawauchi S, Rezaie N, Liang HY, Javonillo D, Thach A, Wang S, Collins S, Walker A, Shi KX, Neumann J, Gomez-Arboledas A, Henningfield CM, Hohsfield LA, Mapstone M, Tenner AJ, LaFerla FM, Mortazavi A, MacGregor GR, Green KN. Butler CA, et al. Among authors: neumann j. Alzheimers Dement. 2024 Mar 20. doi: 10.1002/alz.13783. Online ahead of print. Alzheimers Dement. 2024. PMID: 38506634
Early embryonic lethality in complex I associated p.L104P Nubpl mutant mice.
Cheng C, Cleak J, Weiss L, Cater H, Stewart M, Wells S, Columbres RC, Shmara A, Morato Torres CA, Zafar F, Schüle B, Neumann J, Hatchwell E, Kimonis V. Cheng C, et al. Among authors: neumann j. Orphanet J Rare Dis. 2022 Oct 24;17(1):386. doi: 10.1186/s13023-022-02446-y. Orphanet J Rare Dis. 2022. PMID: 36280881 Free PMC article.
1,721 results