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Discovery of Selective Phosphodiesterase 1 Inhibitors with Memory Enhancing Properties.
J Med Chem. 2017 Apr 27;60(8):3472-3483. doi: 10.1021/acs.jmedchem.7b00302. Epub 2017 Apr 13.
J Med Chem. 2017.
PMID: 28406621
Design and Synthesis of Novel and Selective Glycine Transporter-1 (GlyT1) Inhibitors with Memory Enhancing Properties.
Santora VJ, Almos TA, Barido R, Basinger J, Bellows CL, Bookser BC, Breitenbucher JG, Broadbent NJ, Cabebe C, Chai CK, Chen M, Chow S, Chung M, Crickard L, Danks AM, Freestone GC, Gitnick D, Gupta V, Hoffmaster C, Hudson AR, Kaplan AP, Kennedy MR, Lee D, Limberis J, Ly K, Mak CC, Masatsugu B, Morse AC, Na J, Neul D, Nikpur J, Peters M, Petroski RE, Renick J, Sebring K, Sevidal S, Tabatabaei A, Wen J, Yan Y, Yoder ZW, Zook D.
Santora VJ, et al. Among authors: neul d.
J Med Chem. 2018 Jul 26;61(14):6018-6033. doi: 10.1021/acs.jmedchem.8b00372. Epub 2018 Jul 11.
J Med Chem. 2018.
PMID: 29886732
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Azetidine-based selective glycine transporter-1 (GlyT1) inhibitors with memory enhancing properties.
Hudson AR, Santora VJ, Petroski RE, Almos TA, Anderson G, Barido R, Basinger J, Bellows CL, Bookser BC, Broadbent NJ, Cabebe C, Chai CK, Chen M, Chow S, Chung M, Heger L, Danks AM, Freestone GC, Gitnick D, Gupta V, Hoffmaster C, Kaplan AP, Kennedy MR, Lee D, Limberis J, Ly K, Mak CC, Masatsugu B, Morse AC, Na J, Neul D, Nikpur J, Renick J, Sebring K, Sevidal S, Tabatabaei A, Wen J, Xia S, Yan Y, Yoder ZW, Zook D, Peters M, Breitenbucher JG.
Hudson AR, et al. Among authors: neul d.
Bioorg Med Chem Lett. 2020 Jul 15;30(14):127214. doi: 10.1016/j.bmcl.2020.127214. Epub 2020 Apr 25.
Bioorg Med Chem Lett. 2020.
PMID: 32527538
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Design and Synthesis of Novel and Selective Phosphodiesterase 2 (PDE2a) Inhibitors for the Treatment of Memory Disorders.
Gomez L, Massari ME, Vickers T, Freestone G, Vernier W, Ly K, Xu R, McCarrick M, Marrone T, Metz M, Yan YG, Yoder ZW, Lemus R, Broadbent NJ, Barido R, Warren N, Schmelzer K, Neul D, Lee D, Andersen CB, Sebring K, Aertgeerts K, Zhou X, Tabatabaei A, Peters M, Breitenbucher JG.
Gomez L, et al. Among authors: neul d.
J Med Chem. 2017 Mar 9;60(5):2037-2051. doi: 10.1021/acs.jmedchem.6b01793. Epub 2017 Feb 21.
J Med Chem. 2017.
PMID: 28165743
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Dihydroxyphenylisoindoline amides as orally bioavailable inhibitors of the heat shock protein 90 (hsp90) molecular chaperone.
Kung PP, Huang B, Zhang G, Zhou JZ, Wang J, Digits JA, Skaptason J, Yamazaki S, Neul D, Zientek M, Elleraas J, Mehta P, Yin MJ, Hickey MJ, Gajiwala KS, Rodgers C, Davies JF, Gehring MR.
Kung PP, et al. Among authors: neul d.
J Med Chem. 2010 Jan 14;53(1):499-503. doi: 10.1021/jm901209q.
J Med Chem. 2010.
PMID: 19908836
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Identification of novel substrates for human cytochrome P450 2J2.
Lee CA, Neul D, Clouser-Roche A, Dalvie D, Wester MR, Jiang Y, Jones JP 3rd, Freiwald S, Zientek M, Totah RA.
Lee CA, et al. Among authors: neul d.
Drug Metab Dispos. 2010 Feb;38(2):347-56. doi: 10.1124/dmd.109.030270. Epub 2009 Nov 18.
Drug Metab Dispos. 2010.
PMID: 19923256
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In Vitro Kinetic Characterization of Axitinib Metabolism.
Zientek MA, Goosen TC, Tseng E, Lin J, Bauman JN, Walker GS, Kang P, Jiang Y, Freiwald S, Neul D, Smith BJ.
Zientek MA, et al. Among authors: neul d.
Drug Metab Dispos. 2016 Jan;44(1):102-14. doi: 10.1124/dmd.115.065615. Epub 2015 Oct 28.
Drug Metab Dispos. 2016.
PMID: 26512042
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Benzylmorpholine analogs as selective inhibitors of lung cytochrome P450 2A13 for the chemoprevention of lung cancer in tobacco users.
Blake LC, Roy A, Neul D, Schoenen FJ, Aubé J, Scott EE.
Blake LC, et al. Among authors: neul d.
Pharm Res. 2013 Sep;30(9):2290-302. doi: 10.1007/s11095-013-1054-z. Epub 2013 Jun 12.
Pharm Res. 2013.
PMID: 23756756
Free PMC article.
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