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Poly(A)-binding protein is an ataxin-2 chaperone that regulates biomolecular condensates.
Boeynaems S, Dorone Y, Zhuang Y, Shabardina V, Huang G, Marian A, Kim G, Sanyal A, Şen NE, Griffith D, Docampo R, Lasker K, Ruiz-Trillo I, Auburger G, Holehouse AS, Kabashi E, Lin Y, Gitler AD. Boeynaems S, et al. Among authors: sen ne. Mol Cell. 2023 Jun 15;83(12):2020-2034.e6. doi: 10.1016/j.molcel.2023.05.025. Epub 2023 Jun 8. Mol Cell. 2023. PMID: 37295429
Atxn2-CAG100-KnockIn mouse spinal cord shows progressive TDP43 pathology associated with cholesterol biosynthesis suppression.
Canet-Pons J, Sen NE, Arsović A, Almaguer-Mederos LE, Halbach MV, Key J, Döring C, Kerksiek A, Picchiarelli G, Cassel R, René F, Dieterlé S, Fuchs NV, König R, Dupuis L, Lütjohann D, Gispert S, Auburger G. Canet-Pons J, et al. Among authors: sen ne. Neurobiol Dis. 2021 May;152:105289. doi: 10.1016/j.nbd.2021.105289. Epub 2021 Feb 10. Neurobiol Dis. 2021. PMID: 33577922 Free article.
Mid-Gestation lethality of Atxn2l-Ablated Mice.
Key J, Harter PN, Sen NE, Gradhand E, Auburger G, Gispert S. Key J, et al. Among authors: sen ne. Int J Mol Sci. 2020 Jul 20;21(14):5124. doi: 10.3390/ijms21145124. Int J Mol Sci. 2020. PMID: 32698485 Free PMC article.
Revisiting the complex architecture of ALS in Turkey: Expanding genotypes, shared phenotypes, molecular networks, and a public variant database.
Tunca C, Şeker T, Akçimen F, Coşkun C, Bayraktar E, Palvadeau R, Zor S, Koçoğlu C, Kartal E, Şen NE, Hamzeiy H, Özoğuz Erimiş A, Norman U, Karakahya O, Olgun G, Akgün T, Durmuş H, Şahin E, Çakar A, Başar Gürsoy E, Babacan Yıldız G, İşak B, Uluç K, Hanağası H, Bilgiç B, Turgut N, Aysal F, Ertaş M, Boz C, Kotan D, İdrisoğlu H, Soysal A, Uzun Adatepe N, Akalın MA, Koç F, Tan E, Oflazer P, Deymeer F, Taştan Ö, Çiçek AE, Kavak E, Parman Y, Başak AN. Tunca C, et al. Among authors: sen ne. Hum Mutat. 2020 Aug;41(8):e7-e45. doi: 10.1002/humu.24055. Epub 2020 Jun 24. Hum Mutat. 2020. PMID: 32579787
17 results