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RNA sequencing unravels novel L cell constituents and mechanisms of GLP-1 secretion in human gastric bypass-operated intestine.
Miskelly MG, Lindqvist A, Piccinin E, Hamilton A, Cowan E, Nergård BJ, Del Giudice R, Ngara M, Cataldo LR, Kryvokhyzha D, Volkov P, Engelking L, Artner I, Lagerstedt JO, Eliasson L, Ahlqvist E, Moschetta A, Hedenbro J, Wierup N. Miskelly MG, et al. Among authors: nergard bj. Diabetologia. 2024 Feb;67(2):356-370. doi: 10.1007/s00125-023-06046-8. Epub 2023 Nov 30. Diabetologia. 2024. PMID: 38032369 Free PMC article.
Ghrelin suppresses insulin secretion in human islets and type 2 diabetes patients have diminished islet ghrelin cell number and lower plasma ghrelin levels.
Lindqvist A, Shcherbina L, Prasad RB, Miskelly MG, Abels M, Martínez-Lopéz JA, Fred RG, Nergård BJ, Hedenbro J, Groop L, Hjerling-Leffler J, Wierup N. Lindqvist A, et al. Among authors: nergard bj. Mol Cell Endocrinol. 2020 Jul 1;511:110835. doi: 10.1016/j.mce.2020.110835. Epub 2020 May 3. Mol Cell Endocrinol. 2020. PMID: 32371087 Free article.