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Gut microbiota drives age-related oxidative stress and mitochondrial damage in microglia via the metabolite N6-carboxymethyllysine.
Mossad O, Batut B, Yilmaz B, Dokalis N, Mezö C, Nent E, Nabavi LS, Mayer M, Maron FJM, Buescher JM, de Agüero MG, Szalay A, Lämmermann T, Macpherson AJ, Ganal-Vonarburg SC, Backofen R, Erny D, Prinz M, Blank T. Mossad O, et al. Among authors: nent e. Nat Neurosci. 2022 Mar;25(3):295-305. doi: 10.1038/s41593-022-01027-3. Epub 2022 Mar 3. Nat Neurosci. 2022. PMID: 35241804
Specification of CNS macrophage subsets occurs postnatally in defined niches.
Masuda T, Amann L, Monaco G, Sankowski R, Staszewski O, Krueger M, Del Gaudio F, He L, Paterson N, Nent E, Fernández-Klett F, Yamasaki A, Frosch M, Fliegauf M, Bosch LFP, Ulupinar H, Hagemeyer N, Schreiner D, Dorrier C, Tsuda M, Grothe C, Joutel A, Daneman R, Betsholtz C, Lendahl U, Knobeloch KP, Lämmermann T, Priller J, Kierdorf K, Prinz M. Masuda T, et al. Among authors: nent e. Nature. 2022 Apr;604(7907):740-748. doi: 10.1038/s41586-022-04596-2. Epub 2022 Apr 20. Nature. 2022. PMID: 35444273
Author Correction: Specification of CNS macrophage subsets occurs postnatally in defined niches.
Masuda T, Amann L, Monaco G, Sankowski R, Staszewski O, Krueger M, Del Gaudio F, He L, Paterson N, Nent E, Fernández-Klett F, Yamasaki A, Frosch M, Fliegauf M, Bosch LFP, Ulupinar H, Hagemeyer N, Schreiner D, Dorrier C, Tsuda M, Grothe C, Joutel A, Daneman R, Betsholtz C, Lendahl U, Knobeloch KP, Lämmermann T, Priller J, Kierdorf K, Prinz M. Masuda T, et al. Among authors: nent e. Nature. 2022 Oct;610(7930):E1. doi: 10.1038/s41586-022-05361-1. Nature. 2022. PMID: 36131025 No abstract available.
Microbiota-dependent increase in δ-valerobetaine alters neuronal function and is responsible for age-related cognitive decline.
Mossad O, Nent E, Woltemate S, Folschweiller S, Buescher JM, Schnepf D, Erny D, Staeheli P, Bartos M, Szalay A, Stecher B, Vital M, Sauer JF, Lämmermann T, Prinz M, Blank T. Mossad O, et al. Among authors: nent e. Nat Aging. 2021 Dec;1(12):1127-1136. doi: 10.1038/s43587-021-00141-4. Epub 2021 Dec 20. Nat Aging. 2021. PMID: 37117525