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Smoothened transduces Hedgehog signals via activity-dependent sequestration of PKA catalytic subunits.
PLoS Biol. 2021 Apr 22;19(4):e3001191. doi: 10.1371/journal.pbio.3001191. eCollection 2021 Apr.
PLoS Biol. 2021.
PMID: 33886552
Free PMC article.
Studies of SMOOTHENED Activation in Cell-Free and Reconstituted Systems.
Nelson IB, Myers BR.
Nelson IB, et al.
Methods Mol Biol. 2022;2374:161-174. doi: 10.1007/978-1-0716-1701-4_14.
Methods Mol Biol. 2022.
PMID: 34562251
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A PKA inhibitor motif within SMOOTHENED controls Hedgehog signal transduction.
Happ JT, Arveseth CD, Bruystens J, Bertinetti D, Nelson IB, Olivieri C, Zhang J, Hedeen DS, Zhu JF, Capener JL, Bröckel JW, Vu L, King CC, Ruiz-Perez VL, Ge X, Veglia G, Herberg FW, Taylor SS, Myers BR.
Happ JT, et al. Among authors: nelson ib.
Nat Struct Mol Biol. 2022 Oct;29(10):990-999. doi: 10.1038/s41594-022-00838-z. Epub 2022 Oct 6.
Nat Struct Mol Biol. 2022.
PMID: 36202993
Free PMC article.
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Synthesis and characterization of novel calcium phosphate glass-derived cements for vital pulp therapy.
Howard J, Gardner L, Saifee Z, Geleil A, Nelson I, Colombo JS, Naleway SE, Carlson K.
Howard J, et al.
J Mater Sci Mater Med. 2020 Jan 2;31(1):12. doi: 10.1007/s10856-019-6352-5.
J Mater Sci Mater Med. 2020.
PMID: 31897754
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GRK2 Kinases in the Primary Cilium Initiate SMOOTHENED-PKA Signaling in the Hedgehog Cascade.
Walker MF, Zhang J, Steiner W, Ku PI, Zhu JF, Michaelson Z, Yen YC, Lee A, Long AB, Casey MJ, Poddar A, Nelson IB, Arveseth CD, Nagel F, Clough R, LaPotin S, Kwan KM, Schulz S, Stewart RA, Tesmer JJG, Caspary T, Subramanian R, Ge X, Myers BR.
Walker MF, et al. Among authors: nelson ib.
bioRxiv [Preprint]. 2024 Apr 18:2023.05.10.540226. doi: 10.1101/2023.05.10.540226.
bioRxiv. 2024.
PMID: 37214942
Free PMC article.
Preprint.
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