Nelson EA - Search Results

1

CDK5RAP3 is a co-factor for the oncogenic transcription factor STAT3.

Egusquiaguirre SP, Liu S, Tošić I, Jiang K, Walker SR, Nicolais M, Saw TY, Xiang M, Bartel K, Nelson EA, Frank DA. Egusquiaguirre SP, et al. Among authors: nelson ea. Neoplasia. 2020 Jan;22(1):47-59. doi: 10.1016/j.neo.2019.10.002. Epub 2019 Nov 22. Neoplasia. 2020. PMID: 31765941 Free PMC article.

2

Reciprocal effects of STAT5 and STAT3 in breast cancer.

Walker SR, Nelson EA, Zou L, Chaudhury M, Signoretti S, Richardson A, Frank DA. Walker SR, et al. Among authors: nelson ea. Mol Cancer Res. 2009 Jun;7(6):966-76. doi: 10.1158/1541-7786.MCR-08-0238. Epub 2009 Jun 2. Mol Cancer Res. 2009. PMID: 19491198

3

Microtubule-targeted chemotherapeutic agents inhibit signal transducer and activator of transcription 3 (STAT3) signaling.

Walker SR, Chaudhury M, Nelson EA, Frank DA. Walker SR, et al. Among authors: nelson ea. Mol Pharmacol. 2010 Nov;78(5):903-8. doi: 10.1124/mol.110.066316. Epub 2010 Aug 6. Mol Pharmacol. 2010. PMID: 20693278

4

STAT5 outcompetes STAT3 to regulate the expression of the oncogenic transcriptional modulator BCL6.

Walker SR, Nelson EA, Yeh JE, Pinello L, Yuan GC, Frank DA. Walker SR, et al. Among authors: nelson ea. Mol Cell Biol. 2013 Aug;33(15):2879-90. doi: 10.1128/MCB.01620-12. Epub 2013 May 28. Mol Cell Biol. 2013. PMID: 23716595 Free PMC article.

5

STAT5 represses BCL6 expression by binding to a regulatory region frequently mutated in lymphomas.

Walker SR, Nelson EA, Frank DA. Walker SR, et al. Among authors: nelson ea. Oncogene. 2007 Jan 11;26(2):224-33. doi: 10.1038/sj.onc.1209775. Epub 2006 Jul 3. Oncogene. 2007. PMID: 16819511

6

Isolation of unique STAT5 targets by chromatin immunoprecipitation-based gene identification.

Nelson EA, Walker SR, Alvarez JV, Frank DA. Nelson EA, et al. J Biol Chem. 2004 Dec 24;279(52):54724-30. doi: 10.1074/jbc.M408464200. Epub 2004 Oct 20. J Biol Chem. 2004. PMID: 15498775 Free article.

7

Identification of human STAT5-dependent gene regulatory elements based on interspecies homology.

Nelson EA, Walker SR, Li W, Liu XS, Frank DA. Nelson EA, et al. J Biol Chem. 2006 Sep 8;281(36):26216-24. doi: 10.1074/jbc.M605001200. Epub 2006 Jul 13. J Biol Chem. 2006. PMID: 16840779 Free PMC article.

8

Nifuroxazide inhibits survival of multiple myeloma cells by directly inhibiting STAT3.

Nelson EA, Walker SR, Kepich A, Gashin LB, Hideshima T, Ikeda H, Chauhan D, Anderson KC, Frank DA. Nelson EA, et al. Blood. 2008 Dec 15;112(13):5095-102. doi: 10.1182/blood-2007-12-129718. Epub 2008 Sep 29. Blood. 2008. PMID: 18824601 Free PMC article.

9

A chemical biology approach to developing STAT inhibitors: molecular strategies for accelerating clinical translation.

Nelson EA, Sharma SV, Settleman J, Frank DA. Nelson EA, et al. Oncotarget. 2011 Jun;2(6):518-24. doi: 10.18632/oncotarget.296. Oncotarget. 2011. PMID: 21680956 Free PMC article. Review.

10

The STAT5 Inhibitor Pimozide Displays Efficacy in Models of Acute Myelogenous Leukemia Driven by FLT3 Mutations.

Nelson EA, Walker SR, Xiang M, Weisberg E, Bar-Natan M, Barrett R, Liu S, Kharbanda S, Christie AL, Nicolais M, Griffin JD, Stone RM, Kung AL, Frank DA. Nelson EA, et al. Genes Cancer. 2012 Jul;3(7-8):503-11. doi: 10.1177/1947601912466555. Genes Cancer. 2012. PMID: 23264850 Free PMC article.

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